Comparable to citalopram. By continuing to browse this site, you agree to its use of cookies as described in our I have read and accept the Wiley Online Library Terms and Conditions of UseYears lived with disability (YLDs) for 1160 sequelae of 289 diseases and injuries 1990‐2010: a systemic analysis for the Global Burden of Disease Study 2010Increased 12‐month prevalence rates of mental disorders in patients with chronic somatic diseasesQuality of life in medically ill persons with comorbid mental disorders: a systematic review and meta‐analysisDepression, antidepressants, and long‐term mortality in heart failureOn the validity of the Beck Depression Inventory. Its pharmacokinetics are as summarised in Table There are also a number of other antidepressants that are established in clinical use that may be of use in this population (see Table Whilst the anxiety about use of antidepressants in the CLD population relates predominantly to pharmacokinetic changes, the concern about their use in the post‐OLT setting is different, focusing particularly on medication tolerability and interactions with other medications, most notably immunosuppressive medications. exacerbation of hepatic encephalopathy. Istock Liver damage can occur within a few days of initiation Antidepressant-induced liver failure can be life threatening Antidepressants with higher risk for liver failure include: iproniazid, nefazodone, phenelzine, imipramine, amitriptyline, duloxetine, bupropion, trazodone, tianeptine, and agomelatine Name must be less than 100 characters eCollection 2019 May.Vu TTM, Le TV, Dang AK, Nguyen LH, Nguyen BC, Tran BX, Latkin CA, Ho CSH, Ho RCM.Int J Environ Res Public Health. Unable to load your collection due to an error Patient profile most likely to benefit Elderly patient, patient with an agitated depression, or patient with GI … A group of French researchers has argued that antidepressant medications, which all carry a risk of liver damage, are more toxic to the liver than past research has suggested, Medscape reports. • Good choice for concomitant insomnia (dose: 7.5-15 mg HS) Your patient has chronic kidney disease (CKD). Epub 2019 Jun 19.Hepatol Commun. Section of Hepatology, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, Paddington, London, UKDr B. Mullish, Section of Hepatology and Gastroenterology, Faculty of Medicine, St Mary's Hospital Campus, Imperial College London, 10th floor, QEQM building, South Wharf Road, Paddington, London, UK.Section of Hepatology, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, Paddington, London, UKSection of Hepatology, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, Paddington, London, UKSection of Hepatology, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, Paddington, London, UKSection of Hepatology, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, Paddington, London, UKDr B. Mullish, Section of Hepatology and Gastroenterology, Faculty of Medicine, St Mary's Hospital Campus, Imperial College London, 10th floor, QEQM building, South Wharf Road, Paddington, London, UK.Section of Hepatology, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, Paddington, London, UKSection of Hepatology, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, Paddington, London, UKSection of Hepatology, Faculty of Medicine, Imperial College London, St Mary's Hospital Campus, Paddington, London, UKUse the link below to share a full-text version of this article with your friends and colleagues. 2019 Sep;33(3):160-164. doi: 10.1007/s40211-019-0314-5.