Available for Android and iOS devices. Fortunately, there are treatment options.When your healthcare professional measures your blood pressure, he or she will tell you two numbers: systolic and diastolic blood pressure. Higher doses of InnoPran XL (160, 640 mg) had no additional blood-pressure lowering effect when compared with 120 mg. Initiate InnoPran XL therapy in patients with impaired hepatic function at the lowest dose (80 mg) once daily and monitor patients for marked bradycardia and hypotension Most overdoses of propranolol are mild and respond to supportive care.Hypotension and bradycardia have been reported following propranolol overdose and should be treated appropriately. Lowering blood pressure reduces the risk of fatal and non-fatal cardiovascular events, primarily strokes and myocardial infarctions. InnoPran XLBlood pressure is determined by the amount of blood your heart pumps and the amount of resistance to blood flow in your arteries. If angina markedly worsens or acute coronary insufficiency develops, promptly resume therapy, at least temporarily and take other measures appropriate for the management of unstable angina. Systolic comes from the ancient Greek word “systole” which means “a drawing together or a contraction.” The normal range for systolic blood pressure is 90 – 120 mmHg in adults. On a body surface area basis, this dose in the mouse and rat is, respectively, about equal to and about twice the MRHD of 640 mg propranolol HCl. They are available as follows:80 mg: A gray/white capsule, imprinted with ‘InnoPran XL’, ‘80’, and 2 segmented bands, is available in bottles of 30 capsules (NDC 62559-590-30) and professional samples of 7 capsules (NDC 62559-590-77).120 mg: A gray/off-white capsule, imprinted with ‘InnoPran XL’, ‘120’, and 3 segmented bands, is available in bottles of 30 capsules (NDC 62559-591-30) and professional samples of 7 capsules (NDC 62559-591-77).For further product information, please visit www.anipharmaceuticals.com or call 1-800-308-6755.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Initiate InnoPran XL therapy in patients with impaired renal function at the lowest dose (80 mg) once daily and monitor patients for marked bradycardia and hypotension The exposure to propranolol is increased in patients with hepatic impairment. For this reason, it is wise to discuss the components of your blood pressure (systolic vs. diastolic) with your healthcare provider to understand what each may mean specifically for you.1. So what does this mean?Systolic blood pressure is the amount of pressure that blood exerts on arteries and vessels while the heart is beating. Most blood pressure medications are taken once daily. At dosages greater than required for beta blockade, propranolol also exerts a quinidine-like or anesthetic-like membrane action, which affects the cardiac action potential. Among factors that contribute to the antihypertensive action are: (1) decreased cardiac output, (2) inhibition of renin release by the kidneys, and (3) diminution of tonic sympathetic nerve outflow from vasomotor centers in the brain. INDICATION: InnoPran XL ® is a beta adrenergic blocker indicated for the treatment of hypertension, to lower blood pressure. These benefits have been seen in controlled trials of antihypertensive drugs from a wide variety of pharmacologic classes, including beta-blockers. Elliot WJ. Initiate dosing at 80 mg and titrate to 120 mg daily as needed for blood pressure control.