Desmopressin has been used for many years in the treatment of diabetes insipidus, nocturnal enuresis (involuntary urination while asleep) and nocturia associated with multiple sclerosis (in adults aged up to 65 years); it has also been recommended in certain circumstances for the treatment of nocturia in men and women (previously, an unlicensed use). While we labelled the dosage as high, low, and very low in this review, actual bioavailability may be different. Weight, sitting and standing blood pressures, serum electrolytes and osmolality, and urinary electrolytes, creatinine level and osmolality were also recorded. Desmopressin reduces the frequency of nocturia induced by nocturnal polyuria.5However, little is known about the use of desmopressin in elderly women with nocturnal polyuria. Exclusion criteria included nocturnal enuresis or incontinence, significant cardiovascular, renal or hepatic disease, diabetes, UTI or concomitant medication active on the lower urinary tract.Twenty patients (mean age 70.5 years, range 52–80) were entered into the study, which was conducted over 7 consecutive weeks and started with a 1‐week placebo run‐in period to establish baseline voiding values. Japanese Journal of Geriatrics, Current Pharmacologic Treatment of Lower Urinary Tract Symptoms, A Contemporary Assessment of Nocturia: Definition, Epidemiology, Pathophysiology, and Management—a Systematic Review and Meta-analysis, Efficacy and safety of desmopressin for treatment of nocturia: a systematic review and meta-analysis of double-blinded trials, Nocturia: A Nonspecific but Bothersome Symptom in Urology, Effect of moxibustion treatment for nocturia: a randomized controlled trial, Zen Nihon Shinkyu Gakkai zasshi (Journal of the Japan Society of Acupuncture and Moxibustion), Meyler's Side Effects of Endocrine and Metabolic Drugs, Nocturia: A non‐specific but important symptom of urological disease, Human Atrial Natriuretic Peptide is a Useful Criterion in Treatment of Nocturia, Uroginecología y cirugía reconstructiva de la pelvis, Use of desmopressin and concomitant use of potentially interacting drugs in elderly patients in Sweden, Dementia and lower urinary dysfunction: With a reference to anticholinergic use in elderly population, Nocturnal polyuria in patients with lower urinary tract symptoms and response to alpha-blocker therapy, Meyler's Side Effects of Drugs: The International Encyclopedia of Adverse Drug Reactions and Interactions, Frequency volume charts should be used in men with lower urinary tract symptoms, Nocturnal polyuria in women with overactive bladder symptoms and nocturia, Nocturnal Polyuria with Abnormal Circadian Rhythm of Plasma Arginine Vasopressin in Post-stroke Patients, The pharmacokinetics of 400 µg of oral desmopressin in elderly patients with nocturia, and the correlation between the absorption of desmopressin and clinical effect, The risk of hyponatremia in older adults using desmopressin for nocturia: A systematic review and meta‐analysis, Nocturia in older people: A review of causes, consequences, assessment and management, Effects of OPC-51803, a Novel, Nonpeptide Vasopressin V2-Receptor Agonist, on Micturition Frequency in Brattleboro and Aged Rats, Relation between nocturnal voiding frequency and nocturnal urine production in older men:a population-based study, Efficacy of desmopressin in treatment of refractory nocturia in patients older than 65 years, Nocturia in men, women and the elderly: a practical approach, The role of desmopressin in the treatment of adult nocturia, A PHARMACOKINETIC AND PHARMACODYNAMIC COMPARISON OF DESMOPRESSIN ADMINISTERED AS WHOLE, CHEWED AND CRUSHED tablets, AND AS AN ORAL SOLUTION, A PHARMACOKINETIC AND PHARMACODYNAMIC COMPARISON OF DESMOPRESSIN ADMINISTERED AS WHOLE, CHEWED AND CRUSHED tablets, AND AS AN ORAL SOLUTION, Relation of nocturnal polyuria of the elderly to essential hypertension, the site you are agreeing to our use of cookies. Find out about Lean Library If you have access to journal via a society or associations, read the instructions belowAccess to society journal content varies across our titles.If you have access to a journal via a society or association membership, please browse to your society journal, select an article to view, and follow the instructions in this box.Contact us if you experience any difficulty logging in.Some society journals require you to create a personal profile, then activate your society accountYou are adding the following journals to your email alertsDid you struggle to get access to this article?