Dihydro-testosterone (DHT) has a key role in mediating progressive scalp hair loss in men with AGA, and finasteride blocks the conversion of testosterone to DHT as a selective type II 5α-reductase inhibitor, which justifies its use in AGA treatment [1-3]. Definitely stick it out if you can :)!Results were noticeable after around 4 months, however they were only minor. Duration: 1 year Rx: Finasteride 1mg PO daily Side effects: Within two weeks of starting the medication, I felt very brief episodes of breast tenderness but those went away quickly. Questionnaire items were as follows. Some improvements in results between years one and two may be accounted for because of improvement of hair quality and length of initially grown hairs throughout the second year as hairs cycle and regrow. Optimal results were shown at about one year after initiating the drug treatment. Finasteride 1mg temporarily reverses hair loss in men with androgenetic alopecia (male pattern baldness). Furthermore, a novel discovery of this study was that the group with N-H:I/II/III at the first visit showed greater improvement than the group with N-H: IV/V/ VI/VII at first visit, following 10 years of AGA treatment with finasteride. In the investigation in 40 years or older of Asians, the incidences of decreased libido and erectile dysfunction were 6.0–38.7% and 40.6–70.0%, respectively [29,23]. For the Norwood-Hamilton classifications, stages IIa and IIv were combined as II, IIIa and IIIv were combined as III, IVa was combined as IV, and Va was combined as V. The proportions of patients with improvement (score ≥ 5) and prevention of disease progression (score ≥ 4) were 91.5% and 99.1%, respectively. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:Notes: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. Placebo 2 Year Hairloss Results Some patients did improve from a slight result after one year to moderate results after two years, and from moderate to great. All adverse reactions were mild and all patients continued treatment for 10 years.We evaluated the long-term (10-year) efficacy and safety of AGA treatment with 1 mg/day finasteride in a large study population (532 patients), as the first study of this kind in Japan, to our knowledge. Finally got on board with the medication after one year and I'm thrilled with the results! Q4: How would you compare your hair loss to the hair of people of the same age pre-treatment? We performed subjective evaluations, using questionnaires administered to patients, in addition to the objective evaluation by doctors. And some men may not see real results for six (or more) months. Methods: In two 1-year, Phase III trials, 1,553 men with MPHL were randomized to receive finasteride 1 mg/day or placebo, and 1,215 men continued in up to four 1-year… 2019 Jun;43(6):2409-2419. doi: 10.3892/ijmm.2019.4149. As adverse reactions were recorded by patients in a subjective questionnaire, the result was thought to be slightly different from the correct number of adverse reactions in this study. This was seen in 90% of the subjects. It may take at least four months of daily use of finasteride before you notice an improvement in your hair loss. After that I noticed a steady increased in density and decrease in shedding up until now. The link between diet and hair growth is still being explored, but that doesn’t mean … etc.No, never used Minoxidil. Epub 2019 Mar 22.Baig MS, Kolasa-Wołosiuk A, Pilutin A, Safranow K, Baranowska-Bosiacka I, Kabat-Koperska J, Wiszniewska B.Int J Environ Res Public Health. BPH is caused by an enlarged prostate. Statistical analyses were performed using Microsoft Excel Statistics program version 2.14; a P<0.05 was considered statistically significant.Adverse reactions were recorded to evaluate safety by questionnaire.The characteristics of all patients evaluated for AGA treatment efï¬cacy were as follows: age at first visit, 37.8 ± 10.0 years; age range, 20–69 years; and values of each N-H at the first visit: I/II/III/IV/V/VI/VII, 6/116/204/124/61/18/3, respectively.The proportions of patients with improvement (MGPA ≥ 5) or prevention of disease progression (MGPA ≥ 4) at treatment year 10 were 91.5% (487/532) and 99.1% (527/532), respectively. 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