"Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.© 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Check with your doctor immediately if any of the following side effects occur while taking fluorouracil topical: Redness and swelling of normal skin Alternatively, you can ask your doctor if there's a comparable medication you can take that doesn't interact with grapefruit.Problems arise because chemicals in the fruit can interfere with the enzymes that break down (metabolize) the medication in your digestive system. Along with its needed effects, fluorouracil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Tell your doctor if you have rare but very serious side effects of Efudex including:The dose of Efudex topical is to apply a small amount of the cream to the area that is to be treated, once or twice daily after cleansing. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. "Product Information. Always ask your doctor or pharmacist when you get a new prescription if it interacts with any foods or other medicines. Available for Android and iOS devices.We comply with the HONcode standard for trustworthy health information - Some side effects of fluorouracil topical may occur that usually Check with your health care professional if any of the following side effects 1. Grapefruit and certain other citrus fruits, such as Seville oranges, can interfere with several kinds of prescription medications.Don't take these interactions lightly. 3. 2. O 0Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Some side effects may not be reported. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Talk to your doctor before taking any prescription or over-the-counter medicines.Efudex topical must not be used during pregnancy. If you take prescription medication, ask your doctor or pharmacist whether your medication interacts with grapefruit or other citrus products.You may need to eliminate grapefruit products from your diet. Types of Psoriasis: Medical Pictures and TreatmentsPsoriasis causes the top layer of skin cells to become inflamed and grow too quickly and flake off.Types of Psoriasis: Medical Pictures and Treatments locally and are often related to an © Efudex Patient Information is supplied by Cerner Multum, Inc. and Efudex Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. A single copy of these materials may be reprinted for noncommercial personal use only. O 03. If experienced, these tend to have a Severe expression . Fluorouracil Topical (fluorouracil topical)." Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Call your doctor for medical advice about side effects. It may harm a fetus. Tolak (fluorouracil topical)." If you have DPD enzyme deficiency and use medications containing fluorouracil, you may develop serious side effects such as stomach pain, bloody diarrhea, vomiting, fever, or chills. Treatment lasts 2-6 weeks depending on the condition being treated. Along with its needed effects, fluorouracil topical may cause some unwanted effects. As a result, the medication may stay in your body for too short or too long a time. Cerner Multum, Inc. "Australian Product Information." O 06. Friday, October 7, 2016. You may report them to the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Otherwise, patients may be at an increased risk of such side effects as orthostatic hypotension. Side effects not requiring immediate medical attention. Cerner Multum, Inc. "UK Summary of Product Characteristics." Lipitor - colesterolo abbassare, lovahexal + Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. You may report side effects to FDA at 1-800-FDA-1088.The most frequent adverse reactions to Efudex occur You may report side effects to FDA at 1-800-FDA-1088.