Skincare treatments from U.S. Dermatology Partners Rockville, formerly DermAssociates Rockville, produces exceptional results. You may report side effects to the FDA at 1-800-332-1088. Selected from data included with permission and copyrighted by First Databank, Inc. Read all information given to you. taken, how much, and when it happened. Keep the medicine container tightly closed when not in use.Use the missed dose as soon as you remember. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Do not use extra medicine to make up the missed dose.Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Do not use fluorouracil topical on your eyelids or in your eyes, nose, or mouth. Warnings. WARNINGS (see boxed WARNING) THE DAILY DOSE OF FLUOROURACIL IS NOT TO EXCEED 800 MG. FLUOROURACIL & FLUOROURACIL PRODRUGS/BRIVUDINE; Full Drug Information. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. It is not known whether fluorouracil topical passes into breast milk or if it could harm a nursing baby. Nervous system. https://www.webmd.com/drugs/2/drug-16269/fluorouracil-topical/details 5-fluorouracil is a nucleobase analogue that is uracil in which the hydrogen at position 5 is replaced by fluorine.It is an antineoplastic agent which acts as an antimetabolite - following conversion to the active deoxynucleotide, it inhibits DNA synthesis (by blocking the conversion of deoxyuridylic acid to thymidylic acid by the cellular enzyme thymidylate synthetase) and so slows tumour growth. Fluorouracil can cause neurotoxicity [48], with an incidence of 5–15% and with all schedules of administration in common use [49, 50].The toxicity is acute in onset and cumulative dose-dependency has not been observed. For more information, see the Drug Information Summary for Fluorouracil Injection. Select one or more newsletters to continue. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Fluorouracil therapy is contraindicated for patients in a poor nutritional state, those with depressed bone marrow function, those with potentially serious infections or those with a known hypersensitivity to fluorouracil. This page contains brief information about topical fluorouracil Wear protective clothing and use sunscreen (SPF 30 or higher) when you are outdoors.This medicine can pass into body fluids (urine, feces, vomit). Fluorouracil is also called 5-FU. Use fluorouracil (systemic) as ordered by your doctor. It is used on the skin to treat skin cancer and certain types of skin conditions that could become cancer. These are not all of the side effects that may occur. FLUOROURACIL, 5-FU (flure oh YOOR a sil) is a chemotherapy agent. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. Version: 3.05.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. If you have questions about side effects, call your doctor. All rights reserved. Fluorouracil should be administered under the supervision of an experienced cancer chemotherapy physician because of the possibility of severe toxic reactions; Patient should be hospitalized for initiation of the therapy because of the risk for severe toxic reactions; This medication contains fluorouracil. Use caution when applying the medicine around these areas.Avoid using other medications on the areas you treat with fluorouracil topical unless your doctor tells you to.Avoid exposure to sunlight or tanning beds.