Adults—100 milligrams (mg) or 10 milliliters (mL) once a day for a minimum of 3 weeks. Prior to initiating treatment with CLOZARIL, a baseline ANC must be obtained. Children—Use and dose must be determined by your doctor. Follow your doctor's orders or the directions on the label. Repeat these steps if your total dose is more than 10 mL. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. The oral liquid is best taken on an empty stomach. You may also take itraconazole with an acidic beverage (eg, non-diet cola) if you are taking it with an antacid. Keep from freezing.Do not keep outdated medicine or medicine no longer needed.Ask your healthcare professional how you should dispose of any medicine you do not use.Portions of this document last updated: Sept. 01, 2020Copyright © 2020 IBM Watson Health. Prevention of recurrence (secondary prophylaxis): 5 mg/kg orally per day. Your infection may not clear up if you stop using the medicine too soon. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Ask your doctor if you have any questions. The baseline ANC must be at least 1500/µL for the general population, and at least 1000/µL for patients with documented Benign Ethnic Neutropenia (BEN). Itraconazole, (Sporanox®, Janssen Pharmaceuticals) a triazole, is highly keratinophilic and lipophilic, and tissue levels of the triazole are several times higher than peak plasma levels.5 As a result, itraconazole tends to reach high concentrations in the epidermis and may persist in the skin for 3-4 weeks depending upon the site of infection, thus creating a therapeutic reservoir.6 Furthermore, itraconazole does not redistribute into the systemic circulation.6 Itraconazole is ac… All rights reserved. Measure the oral liquid with a marked measuring spoon or medicine cup. Different brands and dosage forms may not work the same way. Adults—200 milligrams (mg) once a day for 12 weeks in a row. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. Do not switch from the capsules to the oral liquid unless your doctor tells you to. Use only the brand and the dosage form of this medicine that your doctor prescribed. If you have thrush in the mouth or throat, place 10 milliliters (mL) of the liquid in your mouth, swish for several seconds, then swallow. The patients were randomized into three groups, which were treated with 400 mg itraconazole daily, 200 mg itraconazole daily or placebo, respectively, for 7 days. Keep using this medicine for the full treatment time, even if you feel better after the first few doses. To continue treatment, the ANC must be monitored regularly [see Warnings and Precautions (5.1)]. Sporanox® oral liquid works differently than itraconazole Sporanox® capsules, even at the same dose (number of milligrams). Applies to the following strengths: 100 mg; 200 mg; 10 mg/mL; 250 mg; 65 mgLoading dose: 200 mg orally 3 times a day for the first 3 days of therapyLoading dose: 200 mg orally 3 times a day for the first 3 days of therapyLoading dose: 200 mg orally 3 times a day for the first 3 days of therapyLoading dose: 200 mg orally 3 times a day for the first 3 days of therapyOropharyngeal candidiasis: 200 mg orally once a dayTreatment pulse: 200 mg orally twice a day for 1 weekIDSA Recommendations: 200 mg orally 2 or 3 times a dayVulvovaginal candidiasis: 200 mg orally twice a day for 1 daySome experts recommend adjusting dose based on drug serum levels and/or drug interactions.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Maximum dose: 200 mg/day. Method of treatment discontinuation will vary depending on the patients last ANC: Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. The dose of this medicine will be different for different patients. Total duration of therapy: 3 months; longer therapy may be needed for patients with severe disease, immunosuppression, or primary immunodeficiency syndromes. All rights reserved. The following information includes only the average doses of this medicine. Children—Use and dose must be determined by your doctor. This medicine comes with a patient information leaflet. Select one or more newsletters to continue. Maximum dose: 400 mg/day. Itraconazole capsules and tablets should be taken with a full meal. Available for Android and iOS devices. Our general interest e-newsletter keeps you up to date on a wide variety of health topics.Take this medicine only as directed by your doctor. Prick tests with Malassezia antigens and Candida albicans antigen were carried out at the start of the trial and included positive and negative controls. Read and follow the instructions carefully. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. In addition, they took itraconazole, 200 mg/day, during the first week of the first …