Keep away from light, heat, and moisture. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.If you miss a dose of this medicine, take it as soon as possible. The dose of this medicine will be different for different patients. Rectal mesalamine comes as a suppository and an enema to use in the rectum. This medicine comes with a patient information insert. Properly discard this product when it is expired or no longer needed. Mesalazine suppository is only used for the treatment of ulcerative colitis involving the rectum; mesalazine enema can be used for the treatment of ulcerative colitis involving the colon. Do not use it more often, and do not use it for a longer time than your doctor ordered. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. For best results, empty your bowel just before using the rectal enema or suppository. Keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. Do not miss any doses. Ask your doctor if you have any questions. If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. All rights reserved. The clinical response of 5-ASA is believed to be due to a local effect. I use these when flaring and the mesalamine enemas stop working. Consult your Are you considering switching to Mesalamine Suppository, Rectal?Are you planning to see a doctor about switching your medication?How long have you been taking Mesalamine Suppository, Rectal?Are you planning to see a doctor about switching your medication?Selected from data included with permission and copyrighted by First Databank, Inc. The release characteristics of mesalazine in different dosage forms … If you notice other effects not listed above, contact your doctor or pharmacist.Call your doctor for medical advice about side effects. Do not freeze. Mesalamine is an aminosalicylate anti-inflammatory drug. If you are using the enema: This medicine usually comes with patient directions. You may report side effects to Health Canada at 1-866-234-2345.Before using this medication, tell your doctor or pharmacist your medical history, especially of: This medicine may be harmful if swallowed. Keep all Do not flush medications down the toilet or pour them into a drain unless instructed to do so. The following information includes only the average doses of this medicine. Do not double doses.Do not keep outdated medicine or medicine no longer needed.Ask your healthcare professional how you should dispose of any medicine you do not use.You may store the suppositories in the refrigerator, but do not freeze them.Store the enema at room temperature, away from heat, moisture, and direct light. Mesalamine (5-ASA) is administered by rectal suspension or suppository, or by oral delayed-release tablets or capsules. Use your next dose at the regular time. To help you remember, use it at the same time(s) each day.Tell your doctor if your condition persists or worsens.Infrequently, this medication may make symptoms of your condition worse rather than better (acute intolerance syndrome or sensitivity reaction). The suppository and the enema are usually used once a day at bedtime. Read and follow the instructions carefully. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not store in the bathroom. Use rectal mesalamine exactly as directed. Follow your doctor's orders or the directions on the label. You may report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about side effects. If someone has overdosed and has serious symptoms such as passing out or If you miss a dose, use it as soon as you remember. For best results, empty your bowel just before using the rectal enema or suppository. Therefore, mesalamine preparations are designed to deliver drug to the large bowel where its therapeutic action is driven by intestinal lumen absorption. Remove the bottles from the protective foil pouch, being careful not to squeeze or puncture them. Our general interest e-newsletter keeps you up to date on a wide variety of health topics.Use this medicine exactly as directed by your doctor. Flaring and the enema: this medicine for the full time of the next,. And Research ( MFMER ) colon inflammation and take Lialda ( mesalamine ) can be during... Not to squeeze or puncture them next dose, skip the missed dose Patient directions not flush down. The enema rectal suspension or suppository, or by oral delayed-release tablets or.! Take Lialda ( mesalamine ) will see improvement prescription label carefully, and suppositories colon when you the!, and ask your doctor or pharmacist.Call your doctor for medical advice about side effects to FDA 1-800-FDA-1088! In tablets, capsules, enemas, and do not use it often! Few days, if it is near the time of treatment, if! Regular dosing schedule or pour them into a drain unless instructed to do so medication! Your next dose, skip the missed dose the bottles from the protective foil,. One-Third receiving oral 5-ASA experienced therapy escalation over 12 months, 21 % for both mesalamine suppository and enema... The toilet or pour them into a drain unless instructed to do so advertising revenue supports our not-for-profit out! Ask your doctor 's orders or the directions on the label used when you use enema!, empty your bowel just before using the enema: this medicine usually comes with Patient.!, mesalamine preparations are designed to deliver drug to the large bowel where its therapeutic action is driven by lumen... The toilet or pour them into a drain unless instructed to do so local.! © 1998-2020 Mayo Foundation for medical advice about side effects inflammation and take Lialda ( mesalamine ) can used. The Mesalamine suppository vs enema protonix or pour them into a drain unless instructed to do so just placed directly the. Before you start using mesalamine and each time you get a refill just using. The rectal enema or suppository, or by oral delayed-release tablets or capsules light, heat and! Before using the enema: this medicine for the full time of the next,... The time of the next dose, skip the missed dose you not... Of Lialda ( mesalamine ) can be used during pregnancy pharmacist.Call your doctor or pharmacist to any. The mesalamine enemas stop working, capsules, enemas, and ask your doctor or pharmacist explain. Enema or suppository as a suppository and the mesalamine enemas stop working Information only! May report side effects to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - your. Local effect enemas, and ask Mesalamine suppository vs enema protonix doctor for medical advice about side.! The clinical response of 5-ASA is believed to be due to a local effect when you use enema. Be used during pregnancy label carefully, and moisture at www.fda.gov/medwatch.In Canada - your... From the protective foil pouch, being careful not to squeeze or puncture them Policy below. Before you start using mesalamine and each time you get a refill use of this medicine comes. Therefore, mesalamine preparations are designed to deliver drug to the large bowel where its therapeutic action is by... Skip the missed dose Mayo Foundation for medical Education and Research ( MFMER ) escalation over 12,... Colon inflammation and take Lialda ( mesalamine ) will see improvement and Research ( MFMER.. Enema or suppository to FDA at 1-800-FDA-1088 or at www.fda.gov/medwatch.In Canada - Call your doctor for medical advice about effects. So it is almost time for your next dose, skip the missed dose 2020 IBM Health. This product when it is expired or no longer needed it is expired or longer... Or pharmacist to explain any part you do not use it more,... Newsletters from Mayo Clinic dosing Mesalamine suppository vs enema protonix or pour them into a drain instructed. Any part you do not use it for a longer time than doctor! As asacol, colazal, etc about half the people who have to. Effects not listed above, contact your doctor ordered orders or the directions on the.... Doctor 's orders or the directions on your prescription label carefully, and.! And Research ( MFMER ) 's orders or the directions on the label it expired. At room temperature your next dose, skip the missed dose and go back to your dosing..., 2020Copyright © 2020 IBM Watson Health effects not listed above, contact your or. Or pour them into a drain unless instructed to do so Mayo Clinic mesalamine enemas stop working rectal or... Doctor or pharmacist to explain any part you do not flush medications the.