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2002
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Cardinal Glennon Children’s Hospital **The following guideline refers to surgical prophylaxis and does not apply specifically to treatment. 0000304191 00000 n
The usual recommended daily dosage for pediatric patients is 20 mg/kg/day in divided doses every 8 hours.
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Antimicrobial Normal Dose Renal Dosage Adjustment Based on CrCl Estimate (in ml/min)* Abacavir (ABC) Adult 600 mg PO q24h or 300 mg PO q12h Pediatric 8 mg/kg PO q12h No adjustment necessary. 0000069546 00000 n
For traditional dosing, obtain Trough within 30 min before the next dose and Peak 30 min after 30 min infusion. Goal Peak: 8-10 mcg/mL, synergy 3-4 mcg/mL. and formulary information changes.
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2002
1052532-overview
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Diseases & Conditions
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Diseases & Conditions
Controlled studies in pregnant women show no evidence of fetal risk.Second-generation cephalosporin that binds to one or more of the penicillin-binding proteins, which in turn inhibits cell wall synthesis and results in bactericidal activityHas gram-positive activity that first-generation cephalosporins have and adds activity against Proteus mirabilis, H influenzae, Escherichia coli, Klebsiella pneumoniae, and Moraxella catarrhalisPeak serum concentrations: ~7 mcg/mL (250-mg dose); ~13 mcg/mL (500-mg dose); 23 mcg/mL (1-gram dose)Add 106 mL (125-mg or 250-mg bottle) or 68 mL (375-mg bottle) of water in two portions to dry mixtureEach 5 mL (~1 tsp) will contain 125 mg, 250 mg, and 375 mg of cefaclor depending on package sizeCapsules and oral suspension: Administer without regard to meals; shake oral suspension well before usingExtended-release tablets: Do not chew, crush, or split; administer with or within 1 hr of foodCapsules, extended-release tablets, and dry powder for suspension: Store at 20-25°C (68-77°F)Reconstituted oral suspension: Refrigerate for up to 14 days after mixingAdding plans allows you to compare formulary status to other drugs in the same class.To view formulary information first create a list of plans.
2002
PEDIATRIC DOSING GUIDELINES - MISCELANEOUS DRUG DOSE INTERVAL (hr) Acetazolamide** 5 mg/kg/dose Q6 -24 0.5 - 1 g/kg/dose PRN (5% for hypovolemia, 25% for fluid restriction) 0.05 - 0.1 mg/kg/day (Max: 10 mg) DAILY Aspirin (anti -platelet) < 3 kg: 40.5 mg Twice a week > 3 kg - < 5 kg: 40.5 mg M/W/F > 5 kg < 10 kg: 40.5 mg DAILY
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Antibiotic prescribing guidelines establish standards of care, focus quality improvement efforts, and improve patient outcomes. cefaclor-342494
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https://profreg.medscape.com/px/getpracticeprofile.do?method=getProfessionalProfile&urlCache=aHR0cHM6Ly9yZWZlcmVuY2UubWVkc2NhcGUuY29tL2RydWcvY2VmYWNsb3ItMzQyNDk0 interval dosing See appendix for complete guidelines Timing of levels: Draw trough 30 min prior to 4th dose. 0000232101 00000 n
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