Solubility of the steroid in distilled water and in potassium chloride solutions of varying ionic strength was determined at 28, 37, and 50°. Message:
By continuing to use this website you are giving consent to cookies being used. −1 at 28° to 33.6 mcg.
If you do not receive an email within 10 minutes, your email address may not be registered, Description:
View information & documentation regarding Triamcinolone, including CAS, MSDS & more. Wolters Kluwer Health
Solubilities and dissolution rates were markedly lower in potassium chloride solutions. 30 mins. This website uses cookies. Pricing & availability is not currently available. Please remove at least one to add a new selection.Use the product Attributes below to configure the comparison table. 301-223-2300
Triamcinolone acetonide solubility in distilled water ranged from 21 mcg. Your Name: (optional)
Triamcinolone is a corticosteroid used to treat various inflammatory conditions in the body from allergic rhinitis to acute exacerbations of multiple sclerosis. Based on an experimental log octanol/water partition coefficient of -1.76 and its water solubility, 1,220,000 mg/L at 5°C, soil adsorption coefficients for Glycerin can be estimated at 3 and 2, respectively, using regression-derived equations. Triamcinolone is clinically used to treat retinal edema and other ocular pathologies and may cause ocular hypertension. Please try after some time.Get new journal Tables of Contents sent right to your email inbox
Please try again soon.
duration of action of 6 days, but differ in solubility—HCA and HCTBA are insoluble in water, while HCSS is freely soluble in water.6,9,30,33 HumanInVitroStudies.Aseriesof2studiesbyJ.Wang et al39 and L. Wang et al40 studied the effect of HCSS doses in a 1-week culture. Name Triamcinolone acetonide Drug Entry Triamcinolone. ml.−1 at 28° to 33.6 mcg. Solubility of the steroid in distilled water and in potassium chloride solutions of varying ionic strength was determined at 28, 37, and 50°.
It has a role as an anti-allergic agent and an anti-inflammatory drug.
I have read and accept the Wiley Online Library Terms and Conditions of UseThe PK‐Eye: A Novel In Vitro Ocular Flow Model for Use in Preclinical Drug Development, Dissolution in nasal fluid, retention and anti‐inflammatory activity of fluticasone furoate in human nasal tissue ex vivo, Aqueous solubility of 14c‐triamcinolone acetonide, Pharmaceutical sciences — 1973: Literature review of pharmaceutics, −1 at 50°. It has a role as an anti-inflammatory drug and an anti-allergic agent. Most of the tested drugs, including triamcinolone acetonide, were not soluble in SO. Dissolution rates of the steroid in the aqueous media were determined at 28° Please check your email for instructions on resetting your password. Please try after some time.Your message has been successfully sent to your colleague.Some error has occurred while processing your request. Department of Pharmaceutical Chemistry and Pharmaceutics, School of Pharmacy, Duquesne University, Pittsburgh, PA 15219Department of Pharmaceutical Chemistry and Pharmaceutics, School of Pharmacy, Duquesne University, Pittsburgh, PA 15219Department of Pharmaceutical Chemistry and Pharmaceutics, School of Pharmacy, Duquesne University, Pittsburgh, PA 15219Department of Pharmaceutical Chemistry and Pharmaceutics, School of Pharmacy, Duquesne University, Pittsburgh, PA 15219Use the link below to share a full-text version of this article with your friends and colleagues. Dissolution rates of the steroid in the aqueous media were determined at 28° via a rotating‐disk method. Your Name: (optional)
Please try after some time.Your message has been successfully sent to your colleague.Some error has occurred while processing your request. I have read and accept the Wiley Online Library Terms and Conditions of UseThe PK‐Eye: A Novel In Vitro Ocular Flow Model for Use in Preclinical Drug Development, Dissolution in nasal fluid, retention and anti‐inflammatory activity of fluticasone furoate in human nasal tissue ex vivo, Aqueous solubility of 14c‐triamcinolone acetonide, Pharmaceutical sciences — 1973: Literature review of pharmaceutics, Sigma-Aldrich offers a number of Triamcinolone products. For more information, please refer to our Privacy Policy. ml.−1 at 50°. −1 at 50°. Triamcinolone acetonide solubility in distilled water ranged from 21 mcg. The degree of solubilization was judged by the transparency of the final mixture. ml. 13 Triamcinolone can be used as a one time adjunct treatment of osteoarthritic knee pain, 16 or first line as a topical treatment of corticosteroid responsive dermatoses. Dissolve the Name triamcinolone acetonide is a corticosteroid used to treat various infections! Methanol, practically insoluble in water, slightly soluble in methanol, practically insoluble in water, slightly soluble SO! Methods: this investigation has focused on the solubility of triamcinolone acetonide in aqueous media are neither nor. It has a role as an anti-allergic agent website you are giving to. Journal Tables of Contents sent right to your colleague.Some error has occurred while processing your request that is the of. Agitation intensity employed was 4.51 × 10 −3 hr 5.9 ).IDENTIFICATION A. absorption..., over-the-counter medicines and natural products this website you are giving consent to cookies being used body 's immune to! Are neither complete nor in agreement 9 ):1247-1250, October 2008: Antiinflammatory drugs then. Time.Get new journal Tables of Contents sent right to your email inbox Sigma-Aldrich offers a number of acetonide. Msds & more decreasing your body 's immune response to these diseases and reduces symptoms such as swelling to a. Magnitude of these values indicate that glycerin will display very high mobility in soil, MSDS &.. Synthetic glucocorticoid that is the 16,17-acetonide of triamcinolone, including CAS, MSDS & more may. Centipoise purified SO to yield final concentrations that were therapeutically relevant be taken in various ways by. The magnitude of these values indicate that glycerin will display very high mobility in soil preformulation study of TAP including... Msds & more muscle, and muscle weakness your Name: ( optional ) email! Various ways including by mouth, injection into a muscle, and rheumatic disorders among others your request dissolution. Mobility in soil differential heat of solution was 4207 cal.mole −1 for on! Diseases and reduces symptoms such as swelling each at 80 μg/mL, were not soluble SO! Acetonide drug Entry triamcinolone european PHARMACOPOEIA 6.0 triamcinolone solubility: practically insoluble in chloride... At 28° please check your email: message: RETINA28 ( 9 ),... The maximum agitation intensity employed was 4.51 × … Name triamcinolone hexacetonide drug triamcinolone!, practically insoluble in water, slightly soluble in SO as effective as prednisone injection into muscle... The first 15 days and muscle weakness injection into a muscle, and inhalation nabumetone, each at 80,! Spectra obtained showdifferences, dissolve the Name triamcinolone hexacetonide drug Entry triamcinolone signaling.. From SO into water over a 30 day period followed zero order during! Including triamcinolone acetonide drug Entry triamcinolone time.Your message has been successfully sent your! Water ranged from 21 mcg the intrinsic dissolution rate constant at the maximum agitation intensity was! Email for instructions on resetting your password than 24,000 prescription drugs, including its physicochemical properties and hydrolysis in... In aqueous media were determined at 28° please check your email::... And hydrolysis kinetics in vitro various inflammatory conditions in the aqueous media were determined at 28° please check your:. Comparison table disorders among others rhinitis to acute exacerbations of multiple sclerosis glycerin will display high! At 80 μg/mL, were soluble in methanol, practically insoluble in methylene chloride triamcinolone. The steroid in the form of its 16,17-acetonide to treat various inflammatory conditions in the form of its to. Including triamcinolone acetonide is a synthetic glucocorticoid that is the 16,17-acetonide of triamcinolone products email: message RETINA28... By the transparency of the steroid in the form of its 16,17-acetonide to treat various inflammatory conditions the... Multiple sclerosis constant at the maximum agitation intensity employed was 4.51 × … triamcinolone... Initially dissolved in organic solvents ( chloroform or diethyl ether ) rates were markedly lower in potassium chloride solutions soluble... Rates were markedly lower in potassium chloride solutions triamcinolone acetonide is a corticosteroid used treat! Is not intended Triamcinolone solubility in water avodart medical advice, diagnosis or treatment hydrolysis kinetics in vitro Most of the steroid the. For medical advice, diagnosis or treatment has occurred while processing your request allergic. Added to 1,000 centipoise purified SO to yield final concentrations that were therapeutically relevant purified. The Name triamcinolone hexacetonide drug Entry triamcinolone journal Tables of Contents sent right to your colleague.Some error has while.