Hart, Linda L. Middleton, Robert K. Middleton, Robert K. Nervous system disorders: Dizziness. 1982 May;140:473-4. Cambridge University Press This data will be updated every 24 hours.Your email address will be used in order to notify you when your comment has been reviewed by the moderator and in case the author(s) of the article or the moderator need to contact you directly.Please list any fees and grants from, employment by, consultancy for, shared ownership in or any close relationship with, at any time over the preceding 36 months, any organisation whose interests may be affected by the publication of the response. Hidalgo, Hanneli A. Unterweger, B. Unable to load your delegates due to an error Wolfersdorf, M. COVID-19 is an emerging, rapidly evolving situation. Barnas, Ch. There have been reports of abuse of trihexyphenidyl due to its euphoric and hallucinogenic properties. 1990. and Hinterhuber, H. Hole, G. Hinterhuber, H. Steiner, B. and Check if you have access via personal or institutional loginGeha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva and the Tel Aviv University Sackler School of Medicine, IsraelMood elevating effect of trihexyphenidyl and biperiden in individuals taking antipsychotic medicationAbuse of antiparkinson drug by psychiatric patientsAbuse of antiparkinson drugs, feigning of extrapyramidal symptoms to obtain trihexyphenidylUses and toxicity of Belladonna alkaloids and synthetic anticholinergicsPsychotoxic effects of benzhexol hydrochloride (Artane)Anti-cholinergic toxic psychose in drug abusers treated with benzotropine In addition to the many well-known somatic and psychiatric side effects caused by the drug (Shader and Greenblatt, 1971), including toxic psychosis, trihexyphenidyl has been reported as causing a euphoriant effect (Bolin, 1960; Jellinek, 1977; Parker, 1978; Rubinstein, 1978; Shader and Greenblatt, 1971; Goggin and Solomon, 1979). Clipboard, Search History, and several other advanced features are temporarily unavailable. Fleischhacker, W.W. Keller, F. Haring, Ch. Wolfersdorf, M. 2005;40(4):473-82. doi: 10.1081/ja-200052423.Mahal P, Nishanth KN, Mahapatra A, Sarkar S, Balhara YPS.J Neurosci Rural Pract. Hautzinger, M. Most reports on the abuse of antiparkinsonian drugs among schizophrenic pati … Haring, Ch. 1992. Günther, V. Antabuse (disulfiram) blocks an enzyme that is involved in processing alcohol. 1997 May;10(5):367-83. doi: 10.2165/00002512-199710050-00005. Günther, V. Mowers, Robert M. Schöny, W. Keller, F. 1990. 1987. Close this message to accept cookies or find out how to Trihexyphenidyl (benzhexol, Artane) is an anticholinergic drug widely used among the psychiatric population in order to control extrapyramidal symptoms from the use of anti-psychotic drugs. Katschnig, H. and Stuppäck, Ch. Benztropine and biperiden are known to have caused similar phenomena (Jellinek, 1977; Stephens, 1967). and Barnas, Ch. 1. Trihexyphenidyl abuse: therapeutic implications for negative symptoms of schizophrenia? Trihexyphenidyl (Artane) abuse: euphoriant and anxiolytic. Konieczna, T. Meise, U. Unterweger, B. We use cookies to distinguish you from other users and to provide you with a better experience on our websites. Cambridge University Press Epub 2007 Aug 16.Drugs Aging. Trihexyphenidyl (THP) and other antiparkinsonian drugs are known to be substances of abuse. Etzersdorfer, E. Certainly, as Dr … Hautzinger, M. Check if you have access via personal or institutional loginGeha Psychiatric Hospital, Beilinson Medical Center, Petah Tiqva and the Tel Aviv University Sackler School of Medicine, Israel Katschnig, H. Günther, V. Schöny, W. Fleischhacker, W.W. Indications and dose Parkinson's disease (if used in combination with co-careldopa or co-beneldopa) 2018 Jul-Sep;9(3):428-430. doi: 10.4103/jnrp.jnrp_569_17.Caplan JP, Epstein LA, Quinn DK, Stevens JR, Stern TA.Neuropsychol Rev. 1987. Fisch RZ. Stuppäck, Ch. Middleton, Robert K. König, P. Rittmannsberger, H. Steiner, B. Konieczna, T. Möller, H.-J. Etzersdorfer, E. Etzersdorfer, E. Katschnig, H. 2007 Sep;17(3):363-80. doi: 10.1007/s11065-007-9037-7. Kaminer Y, Munitz H, Wijsenbeek H. PMID: Mcqueen, Kellie D. This pertains to all the authors of the piece, their spouses or partners. Hidalgo, Hanneli A. Hautzinger, M. Wolfersdorf, M. Meise, U. Hart, Linda L. Name must be less than 100 characters Hole, G. The use of trihexyphenidyl as self-medication for depression and use by non-depressed people for euphoria is mentioned en passant in the DSM IV and research on anticholinergic abuse in general has appeared in recent decades. 1990. Nappo SA, de Oliveira LG, Sanchez Zv, Carlini Ede A.Subst Use Misuse.