Call 911 if your symptoms feel life-threatening or if you think you’re having a medical emergency. In initial therapy the dose should be 1mg the first day, 2mg the second day with further increases of 2mg per day at three to five-day intervals until the optimum dose is reached.If patients are already being treated with other parasympathetic inhibitors, trihexyphenidyl should be substituted as part of the therapy. It’s used for long-term treatment of Parkinson’s disease. Trihexyphenidyl is also indicated to control extrapyramidal disorders (eg akathisia manifested by extreme restlessness and dyskinesia characterised by spastic contractions and involuntary movements) due to central nervous system drugs such as reserpine and the phenothiazines.The usual dosage for Parkinsonism is 6-10mg per day although some patients chiefly in the post-encephalitic group may require an average total dose of 12-15mg daily. The peak activity is noted after 2 to 3 hours. Trihexyphenidyl is known as an hallucinogenic agent amongst thrill-seeking adolescents (Rouchell and Dixon, 1977) and among prisoners in the US who abuse the drug either orally or by smoking it as a powder mixed with tobacco (Woody and O'Brien, 1974). Except in the case of vital complications, abrupt discontinuation of the drug should be avoided. The absorption of levodopa may possibly be reduced when used in conjunction with trihexyphenidyl.
Your doctor may also run tests to check the function of your liver and kidneys.There are other drugs available to treat your condition. Includes dosages for Parkinson's Disease and Extrapyramidal Reaction; plus renal, liver and dialysis adjustments. Date of first authorisation/renewal of the authorisationStart typing to retrieve search suggestions. In general, anticholinergic agents should be used with caution in patients who are receiving tricyclic antidepressants or monoamine oxidase inhibitors. It works by slowing down the heart and decreasing the amount of blood it pumps out. It is an antispasmodic drug which exerts a direct inhibitory effect on the parasympathetic nervous system. Adverse reactions reported for each of these patient populations are provided below. Some may be better suited for you than others. involuntary movements (additive antimuscarinic effects) This can cause dry mouth, blurred vision, urinary hesitancy, urinary retention and constipation. healthcare professional. The beta-blocking effects of BYSTOLIC can be reversed by beta agonists, eg, dobutamine or isoproterenol. It comes as an oral solution and an oral tablet.Trihexyphenidyl oral tablet is only available as a generic drug. Applies to the following strengths: 2 mg; 5 mg; 2 mg/5 mLInitial dose: 1 mg orally once; if symptoms are not controlled in a few hours, additional doses should be provided until satisfactory control is achievedUse with caution due to a lack of pharmacokinetic data; start low, titrate conservatively and closely monitorUse with caution due to a lack of pharmacokinetic data; start low, titrate conservatively and closely monitorElderly: Patients over 60 years have shown greater sensitivity to the action of parasympatholytic drugs; therefore, initial doses should be low and patients should be monitored closelyAlways consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Additionally, difficulty in restarting and maintaining the heartbeat has been reported with beta blockers.