If these occur, In this same cohort, the incidence of death in the first year post-MI was 20 per 100 person years in NSAID-treated patients compared to 12 per 100 person years in non-NSAID exposed patients. Do not use NSAIDs for a condition for which it was not prescribed. The optimum times for making the first and subsequent transaminase measurements are not known. Inform patients, families, or their caregivers of the following information before Because elderly patients are more likely to have decreased renal function, care should be taken in dose selection, and it may be useful to monitor renal function (See Manage patients with symptomatic and supportive care following an NSAID overdosage. Both diclofenac and its oxidative metabolites undergo glucuronidation or sulfation followed by Diclofenac is eliminated through metabolism and subsequent urinary and biliary excretion of the glucuronide and the sulfate conjugates of the metabolites. Do not take extra medicine to make up the missed dose.Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.Avoid drinking alcohol. pruritus, diarrhea, jaundice, right upper quadrant tenderness, and “flu-like” symptoms). Voltaren is a prescription medicine used to treat symptoms of pain associated with rheumatoid arthritis, osteoarthritis, ankylosing spondylitis, dysmenorrhea, and mild-to-moderate pain. In the general U.S. population, all clinically recognized pregnancies, regardless of drug exposure, have a background rate of 2-4% for major malformations, and 15-20% for pregnancy loss. Select one or more newsletters to continue. Other drugs may interact with diclofenac, including prescription and over-the-counter medicines, Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Voltaren only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2020 Cerner Multum, Inc. diclofenac sodium. Do not use this medicine just before or after heart bypass surgery (coronary artery bypass graft, or CABG).You should not use Voltaren if you are allergic to diclofenac, or if you have ever had an To make sure this medicine is safe for you, tell your doctor if you have:It may not be safe to breastfeed while using this medicine. If you're taking gastro-resistant diclofenac tablets, don't take antacids (indigestion remedies) at the same time of day. The metabolites include 4'hydroxy-, 5-hydroxy-, 3'-hydroxy-, 4',5-dihydroxy- and 3'-hydroxy-4'-methoxy-diclofenac. If the doctor did not discuss this it might be wise to find a better doctor. You may report side effects to FDA at 1-800-FDA-1088.The inactive ingredients in VOLTAREN include: hydroxypropyl methylcellulose, iron oxide, lactose, magnesium stearate, methacrylic acid copolymer, microcrystalline cellulose, polyethylene glycol, povidone, propylene glycol, sodium hydroxide, sodium starch glycolate, talc, titanium dioxide.Carefully consider the potential benefits and risks of VOLTARENCarefully consider the potential benefits and risks of VOLTARENAfter observing the response to initial therapy with VOLTAREN, the dose and frequency should be adjusted to suit an individual patient’s needs.For the relief of osteoarthritis, the recommended dosage is 100-150 mg/day in divided doses (50 mg twice a day or three times a day, or 75 mg twice a day).75 mg - light pink, biconvex, triangular-shaped, enteric-coated tablets (imprinted VOLTAREN 75 on For more information, ask your healthcare provider or pharmacist about NSAIDs.Call your doctor for medical advice about side effects. Swallow the tablets with a full glass of water. This modest dose of voltaren (diclofenac) carries relatively low risk. healthcare provider immediately (see Advise patients to report symptoms of ulcerations and bleeding, including epigastric pain, Inform patients of the warning signs and symptoms of hepatotoxicity (e.g., nausea, fatigue, lethargy, Use of diclofenac may blunt the CV effects of several therapeutic agents used to treat these medical conditions (e.g., diuretics, ACE inhibitors, or Avoid the use of VOLTAREN in patients with severe heart failure unless the benefits are expected to outweigh the risk of worsening heart failure. throat). The Voltaren range includes oral (tablet and liquid capsules) and topical (applied to the skin) treatments. Instruct patients to seek immediate emergency help if these occur (see Advise patients to stop VOLTAREN immediately if they develop any type of rash and contact their healthcare provider as soon as possible (see Advise females of reproductive potential who desire pregnancy that NSAIDs, including VOLTAREN, instruct patients to stop VOLTAREN and seek immediate medical therapy (see Inform patients of the signs of an anaphylactic reaction (eg, difficulty breathing, swelling of the face or Diclofenac is a nonsteroidal anti-inflammatory used to treat pain and inflammation that is associated with arthritis.