"Product Information. Monotherapy (Metastatic Colorectal Cancer, Adjuvant Colorectal Cancer, Metastatic Breast Cancer)Table 1 XELODA Dose Calculation According to Body Surface AreaIn Combination With Docetaxel (Metastatic Breast Cancer)Monotherapy (Metastatic Colorectal Cancer, Adjuvant Colorectal Cancer, Metastatic Breast Cancer)In Combination With Docetaxel (Metastatic Breast Cancer)Table 3 Docetaxel Dose Reduction Schedule in Combination with XELODAWe comply with the HONcode standard for trustworthy health information - Xeloda Side Effects by Likelihood and Severity COMMON side effects. Common side effects may include: low blood sugar; nausea, upset stomach; or diarrhea. The side effects of the drug can be a nuisance or in some cases debilitating. Adverse reactions reported in greater than 5% of GLUCOPHAGE treated patients and that were more common than in placebo-treated patients, are listed in Table 1.Diarrhea led to discontinuation of GLUCOPHAGE in 6% of patients. Anemia 2. Contraindicated in patients with DPD deficiency; causes severe toxicity with conventional doses (ie, grade III/IV toxicity and potentially fatal neutropenia, mucositis, and diarrhea) Decreased Neutrophils A Type Of White Blood Cell 4. Patients should be carefully monitored for toxicity and doses of XELODA should be modified as necessary to accommodate individual patient tolerance to treatment The dose of phenytoin and the dose of coumarin-derivative anticoagulants may need to be reduced when either drug is administered concomitantly with XELODA XELODA dose modification scheme as described below (see Dose modifications of XELODA for toxicity should be made according to The dose reduction schedule for docetaxel when used in combination with XELODA for the treatment of metastatic breast cancer is shown in No adjustment to the starting dose of XELODA is recommended in patients with mild renal impairment (creatinine clearance = 51 to 80 mL/min [Cockroft and Gault, as shown below]). Decreased Blood Platelets 3. Here are some common metformin side effects like diarrhea and lactic acidosis. If capecitabine is discontinued, consider increasing the methadone dose until stable drug effects are achieved and monitor for evidence of opioid withdrawal. XELODA tablets should be swallowed whole with water within 30 minutes after a meal. Call your doctor for medical advice about side effects. Select one or more newsletters to continue. Note: This document contains side effect information about capecitabine. Patients receiving concomitant capecitabine and oral coumarin-derivative anticoagulant therapy should be monitored frequently for anticoagulant response (INR or prothrombin time) and the anticoagulant dose should be adjusted accordingly. In Summary. Xeloda (capecitabine) is a drug used to treat breast cancer that has metastasized to other tissues, as well as colon and colorectal cancers that have spread to lymph nodes and other parts of the body. Painful, Red Or Swollen Mouth 5. Most commonly, these are "non-preferred" brand drugs. Roche Laboratories, Nutley, NJ. Drug information provided by: IBM Micromedex. Insufficient data are available to provide a dosage recommendation.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. The results of this study are encouraging and suggest that a year of low-dose Xeloda after surgery and standard chemotherapy for early-stage triple-negative breast cancer can help reduce the risk of recurrence. Glucophage and Glucophage XR (metformin hydrochloride) are oral antihyperglycemic drugs used to treat type 2 Contact your doctor if you experience serious side effects of Glucophage including Glucophage should be given in divided doses with meals while Glucophage XR should generally be given once daily with the evening meal. 1 If XELODA tablets must be cut or crushed, this should be done by a professional trained in safe handling of cytotoxic drugs using appropriate equipment and safety procedures. Metformin is a medication developed to treat Type 2 diabetes that can also aid in weight loss. Glucophage or Glucophage XR should be started at a low dose, with gradual dose escalation, both to reduce The FDA classifies Glucophage as a class-B drug during Glucophage and Glucophage XR may interact with furosemide, nifedipine, cimetidine, ranitidine, amiloride, triamterene, digoxin, Our Glucophage and Glucophage XR Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication. You may report side effects to FDA at 1-800-FDA-1088. Metformin oral tablet is a prescription drug that’s used along with diet and exercise to … Loss Of Appetite 3. Low Energy 4. Available for Android and iOS devices. You may report side effects to FDA at 1-800-FDA-1088.Some people using metformin develop lactic acidosis, which can be fatal. Cerner Multum, Inc. "Australian Product Information." Throwing Up 7. Xeloda Drug Information / Drug Summary email print Close window. 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