AIDSinfo. Clin Ther 23 (2001): 1603-1412. Ribaudo HJ, Benson CA, Zheng Y, et al. Boyson SJ "Psychiatric effects of selegiline." National Institutes of Health "Guidelines for the use of antiretroviral agents in HIV-1-infected adults and adolescents. You may report side effects to FDA at 1-800-FDA-1088.The number of patients who received selegiline in prospectively monitored pre-marketing studies is limited. Available from: URL: http://aidsinfo.nih.gov/contentfiles/lvguidelines/adultandadolescentgl.pdf." Can J Neurol Sci 19 (1992): 142-68. Arch Neurol 48 (1991): 90210. Clin Infect Dis 53 (2011): 84-9150. Transient high and bruxism were reported at doses greater than 10 mg per day.Anxiety was reported as a very common side effect with selegiline in double-blind placebo-controlled clinical trials when used as adjunctive therapy with levodopa in the earlier phases of Parkinson's disease.Adult and pediatric patients receiving antidepressants for MDD, as well as for psychiatric and nonpsychiatric indications, have reported symptoms that may be precursors to emerging suicidality, including anxiety, agitation, There have been reports of falling asleep while engaged in activities of daily living, including the operation of motor vehicles, which sometimes resulted in accidents, in Parkinson's disease patients treated with this drug. Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Bart PA, Rizzardi GP, Tambussi G, Chave JP, Chapuis AG, Graziois C, Corpataux JM, Halkic N, Meuwly JY, Munoz M, Meylan P, "Immunological and virological responses in HIV-1-infected adults at early stage of established infection treated with highly active antiretroviral therapy." Almost all reactions have included fever and/or rash (usually maculopapular or urticarial); however, reactions also reported without fever or rash. Rauch A, Nolan D, Martin A, McKinnon E, Almeida C, Mallal S "Prospective genetic screening decreases the incidence of abacavir hypersensitivity reactions in the Western Australian HIV cohort study." Strategies for Management of Anti-RetroviralTherapy/Insight; DAD Study Groups "Use of nucleoside reverse transcriptase inhibitors and risk of myocardial infarction in HIV-infected patients." Symptoms of hypersensitivity include rash, vomiting, and shortness of breath. Yokogawa N, Alcid DV "Acute fibrinous and organizing pneumonia as a rare presentation of abacavir hypersensitivity reaction." "Abacavir hypersensitivity reaction in primary HIV infection." AIDS 24 (2010): 2138-943. Barber TJ, Marett B, Waldron S, et al. O 03. Golbe LI "Long-term efficacy and safety of deprenyl (selegiline) in advanced Parkinson's disease." Med Lett Drugs Ther 43 (2001): 103-813. Abacavir is contraindicated in patients with a prior hypersensitivity reaction to abacavir and in HLA-B*5701-positive patients. Abacavir and lamivudine belong to a class of medications known as nucleoside reverse transcriptase inhibitors (NRTIs). Clin Neuropharmacol 23 (2000): 271-52. If you notice other effects not listed above, contact your doctor or pharmacist.In the US -Call your doctor for medical advice about side effects. These side effects may go away during treatment as your body adjusts to the medicine. Parkinson's disease is only seen in people of advanced age. Vandekerckhove L, Blot S "Abacavir hypersensitivity." Abacavir hypersensitivity was reported in about 8% of patients in 9 clinical trials with abacavir-containing products where patients were not screened for the HLA-B*5701 allele; incidence of suspected abacavir hypersensitivity reactions was 1% in clinical trials where HLA-B*5701 carriers were excluded.Abacavir hypersensitivity reactions have been characterized by at least 2 of the following key signs/symptoms: (1) fever; (2) rash; (3) gastrointestinal symptoms (including nausea, vomiting, diarrhea, abdominal pain); (4) constitutional symptoms (including generalized malaise, fatigue, achiness); (5) respiratory symptoms (including dyspnea, cough, pharyngitis). Vezina P, Mohr E, Grimes D "Deprenyl in Parkinson's disease: mechanisms, neuroprotective effect, indications and adverse effects."