Usual Adult Dose for Acute Mountain Sickness. Available for Android and iOS devices. The design was a double-blind, randomized trial of two doses of acetazolamide (125 mg twice daily, 250 mg twice daily) versus placebo twice daily over a 24-h period.
eCollection 2016.Int J Clin Exp Med.
Name must be less than 100 characters The 250-mg dose of acetazolamide twice daily (but not 125 mg twice daily) was effective in inducing a significant decline in AMS symptoms over the 24-h period after arrival to 3630 m. These results suggest that the dosing of acetazolamide for AMS prevention in nonmountaineering tourists at altitudes below 3700 m should not be lowered below 250 mg twice daily.
Acetazolamide in doses of 250 mg, 500 mg, and 750 mg daily are all more effective than placebo for preventing acute mountain sickness. The 250-mg dose of acetazolamide twice daily (but not 125 mg twice daily) was effective in inducing a significant decline in AMS symptoms over the 24-h period after arrival to 3630 m. These results suggest that the dosing of acetazolamide for AMS prevention in nonmountaineering tourists at altitudes below 3700 m should not be lowered below 250 mg twice daily.
Current recommended dosing is 125 mg, orally twice daily, started 24 hours prior to ascending in elevation. Basnyat B, Gertsch JH, Johnson EW, Castro-Marin F, Inoue Y, Yeh C.High Alt Med Biol. There are risks associated with high altitude i…
Travelling to destinations at high altitude can be exciting, challenging and rewarding. Applies to the following strengths: 500 mg; 125 mg; 250 mgInitial dose: 8 to 30 mg/kg orally/IV in divided dosesContraindicated in marked renal disease or impairment (specific CrCl level not provided, however, less than 10 mL/min has been provided by some authorities)Contraindicated in marked liver disease of impairmentElderly: Dose selection should be cautious usually starting at the low end of the dosing rangeSafety and efficacy of extended-release (ER) capsules have not been established in patients younger than 12 years.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.
Side effects include tingling of the fingers and toes and perioral numbness which may be erroneously interpreted as stroke symptoms. 2008 Winter;9(4):289-93. doi: 10.1089/ham.2008.1029.High Alt Med Biol.
If, after an initial response, the patient fails to continue to lose oedema fluid, do not increase the dose but allow for kidney recovery by omitting a day.
Epub 2012 Jul 30.Low EV, Avery AJ, Gupta V, Schedlbauer A, Grocott MP.BMJ. The absolute change in these mean scores was not significant for placebo (p = 0.21) or the 125-mg dose (p = 0.88), but was significant for the 250-mg dose (p = 0.008). Atypon
2012 Sep-Oct;19(5):298-307. doi: 10.1111/j.1708-8305.2012.00629.x. 2012 Oct 18;345:e6779. He asks you for a prescription of acetazolamide to prevent mountain sickness. 2017 Jun 27;6(6):CD009761. Please enable it to take advantage of the complete set of features!
doi: 10.1002/14651858.CD009761.pub2.Elisabeth E, Hannes G, Johannes B, Martin F, Elena P, Martin B.Int J Physiol Pathophysiol Pharmacol.
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Good medical insurance that covers medical evacuation and repatriation is strongly recommended for those travelling to area of high altitude. Adults: For diuresis, the starting dose is usually 250 - 375mg (1-1½ tablets) once daily in the morning. DOSE; Acetazolamide: AMS, HACE prevention: Oral: 125 mg twice a day; 250 mg twice a day if >100 kg. 2016 Jun 1;74:23. doi: 10.1186/s13690-016-0134-z. 2017 Apr 15;9(2):28-34. eCollection 2017.Gonggalanzi, Labasangzhu, Nafstad P, Stigum H, Wu T, Haldorsen ØD, Ommundsen K, Bjertness E.Arch Public Health.
Acetazolamide 125 mg twice daily can be prescribed as prophylaxis for those at risk of developing acute mountain sickness A 25 year old man plans to trek to Everest Base Camp (5545 m) in Nepal for charity. 2003 Spring;4(1):45-52. doi: 10.1089/152702903321488979.van Patot MC, Leadbetter G 3rd, Keyes LE, Maakestad KM, Olson S, Hackett PH.High Alt Med Biol. 2008 Spring;9(1):15-23. doi: 10.1089/ham.2007.1037.J Travel Med. 2014 Nov 15;7(11):4378-83. eCollection 2014.
doi: 10.1136/bmjresp-2020-000557.Nieto Estrada VH, Molano Franco D, Medina RD, Gonzalez Garay AG, Martí-Carvajal AJ, Arevalo-Rodriguez I.Cochrane Database Syst Rev.
Volunteers vacationing in La Paz, Bolivia (3630 m), immediately after arrival from sea level were studied.