See The following adverse reactions have been reported coincident with the administration of methocarbamol. Althea pills have the same active ingredients as another popular contraceptive pill brand, Diane 35, and other lesser-known pills like Dinac 35, Elestra, Elyn, Frualine, Ginetta, Ancea, and MyPill. The injections may be repeated at eight hour intervals, if necessary. Call your doctor for medical advice about side effects. Rate of injection should not exceed 3 mL per minute–i.e., one 10 mL vial in approximately three minutes. Although the amount present in this preparation is well within the limits of safety, caution dictates this contraindication.Robaxin Injectable is contraindicated in patients hypersensitive to methocarbamol or to any of the injection components.Since methocarbamol may possess a general CNS depressant effect, patients receiving Robaxin Injectable should be cautioned about combined effects with alcohol and other CNS depressants.Safe use of Robaxin Injectable has not been established with regard to possible adverse effects upon fetal development. A recumbent position will reduce the likelihood of side reactions.Blood aspirated into the syringe does not mix with the hypertonic solution. This caution is necessary because of the presence of polyethylene glycol 300 in the vehicle.A much larger amount of polyethylene glycol 300 than is present in recommended doses of Robaxin Injectable is known to have increased pre-existing acidosis and urea retention in patients with renal impairment. The percent of methocarbamol bound to plasma proteins was decreased to approximately 40 to 45% compared to 46 to 50% in the normal subjects.The injectable form of methocarbamol is indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomfort associated with acute, painful musculoskeletal conditions. This phenomenon occurs with many other intravenous preparations. You may report side effects to FDA at 1-800-FDA-1088.Other drugs may interact with methocarbamol, including prescription and over-the-counter medicines, Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Robaxin only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2020 Cerner Multum, Inc. Version: 8.01.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. When satisfactory relief of symptoms is achieved, it can usually be maintained with tablets.There is clinical evidence which suggests that methocarbamol may have a beneficial effect in the control of the neuromuscular manifestations of tetanus. The fraction of bound methocarbamol was slightly decreased in the elderly versus younger volunteers (41 to 43% versus 46 to 50%, respectively).The clearance of methocarbamol in 8 renally-impaired patients on maintenance hemodialysis was reduced about 40% compared to 17 normal subjects, although the mean (± SD) elimination half-life in these two groups was similar (1.2 (± 0.6) versus 1.1 (± 0.3) hours, respectively).In 8 patients with cirrhosis secondary to alcohol abuse, the mean total clearance of methocarbamol was reduced approximately 70% compared to that obtained in 8 age- and weight-matched normal subjects. Because many drugs are excreted in human milk, caution should be exercised when Robaxin Injectable is administered to a nursing woman.Safety and effectiveness of Robaxin Injectable in pediatric patients have not been established except in tetanus. The pH is adjusted, when necessary, with hydrochloric acid and/or sodium hydroxide. In case of overdose, get medical help or contact a Poison Control Center immediately.