2019 Aug;75(8):1117-1124. doi: 10.1007/s00228-019-02668-3. Objective: To describe the prevalence of hyponatremia in older adults related to antidepressive agents and identify potential alternative options in older adults with a low-baseline serum sodium concentration and/or when a patient has experienced hyponatremia as a result of taking an antidepressant. lithium, antidepressants. In contrast, antidepressants are known to cause hyponatremia, particularly in the elderly. Whether all antidepressants cause hyponatremia equally has been questioned 3 but is still controversial after multiple population-based studies published in recent years. Name must be less than 100 characters This site needs JavaScript to work properly. While these drugs are highly effective in treating depression, they are often associated with side effects such as headaches, weight gain and sexual dysfunction 1 3. Individuals all respond differently so it is not possible to make any such definitive statement. Mannesse did not respond to a request for comments. Please enable it to take advantage of the complete set of features! We’ll go over and compare the common side effects associated with different types of antidepressants. Independent risk factors for hyponatremia on multivariate analysis included a history of hyponatremia, weight below 60 kg, and symptoms of psychosis (in most patients as part of depression). Antidepressant-induced hyponatraemia can cause significant morbidity, complications and mortality. Close more info about Which Antidepressants Are Linked to Greater Hyponatremia Risk? It helps control symptoms of acute mania. © 2020 Psychiatry & Behavioral Health Learning Network is a trademark of HMP. doi: 10.1097/MD.0000000000013178. Always seek the advice of a qualified physician for medical diagnosis and treatment. Every tooth in my mouth has a crown on it due to cavities from having dry mouth. Objective: To describe the prevalence of hyponatremia in older adults related to antidepressive agents and identify potential alternative options in older adults with a low-baseline serum sodium concentration and/or when a patient has experienced hyponatremia as a result of taking an antidepressant. "Instead, nephrogenic syndrome of inappropriate antidiuresis was a more common cause, probably as a result of an increase in the sensitivity of the kidney to ADH. "Almost all of the patients with serum sodium levels >135 mM had a normal ADH response," the researchers note. Don't stop taking an antidepressant without talking to your doctor first. 2020 May 7;16:1157-1170. doi: 10.2147/NDT.S241780. A variety of prescription antidepressant drugs are available to treat depression and anxiety disorders. Data sources: A PubMed search was conducted on November 10, 2015. Objectives . Cyndie K. Mannesse from Vlietland Hospital in Schiedam and colleagues analyzed prospectively collected data from 345 elderly (>60 years old) patients who had been treated with antidepressants for at least four days.Over a third (37%) used SSRIs, 23% used tricyclic antidepressants, 21% used mirtazapine, 10% used venlafaxine, 2% used monoamine oxidase inhibitors, and 7% used other antidepressants or combinations of antidepressants, the team found.Thirty-two patients (9.3%) had hyponatremia possibly or probably related to antidepressant therapy. Lithium (such as Lithobid) is a mood-stabilizing drug that’s been used since the 1970s. The incidence of SIADH with selective serotonin reuptake inhibitors (SSRIs) varies greatly among studies, from .06% to 40%. Elsevier Science Int J Clin Pharmacol Ther. Objective To examine the association between classes of antidepressants and hyponatremia, and between specific antidepressants and hyponatremia. Recently, I gained 20 pounds in two weeks on Saphris, an anti-psychotic. Quitting suddenly may cause a sudden worsening of depression. masso 15 Oct 2017 "Best bipolar depression medications. Background: Antidepressant-induced hyponatremia can cause significant morbidity and mortality. Antidepressants. Elsevier Science This is only an anonymous self test.Hyponatremia is an electrolyte imbalance causing low blood sodium levels. Unable to load your delegates due to an error Mirtazapine and tricyclic antidepressants showed a moderate risk of hyponatremia, supporting the use of these drugs as alternative therapy for patients at an increased risk for hyponatremia. Hyponatremia equally has been questioned 3 but is still controversial after multiple population-based studies published in recent.... Between classes of antidepressants and hyponatremia, and between specific antidepressants and hyponatremia wide variation is due to the each! 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