They kill or inactivate fungi and are used to treat fungal infections (including yeast infections). Dulcolax® offers a range of constipation relief tablets and suppositories. 0000002679 00000 n 0000004422 00000 n 0000004921 00000 n 0000032034 00000 n 0000007827 00000 n 0000002946 00000 n %PDF-1.4 %���� 557 0 obj <> endobj Many topical antifungals work by inhibiting production of ergosterol, a fundamental component of the fungal cell membrane and wall. 0000005423 00000 n Antifungal Agents Spectrum of Activity, Pharmacology, and Clinical Indications Jeniel E. Nett, MD, PhDa,b, David R. Andes, MDa,b,* INTRODUCTION: THE EVOLUTION OF ANTIFUNGAL DRUG THERAPY Continued advancement of medical science offers life-saving treatment options for a variety of hematologic, oncologic, and rheumatologic conditions. 0000005167 00000 n 0000009468 00000 n 0000001328 00000 n 0000003924 00000 n 0000002706 00000 n xref 20 34 0000067090 00000 n xref 0000002112 00000 n 0000007395 00000 n 0000004503 00000 n 0000007145 00000 n 0000008996 00000 n < 0000001381 00000 n 0000001641 00000 n 0000001646 00000 n 0000002212 00000 n 0000006769 00000 n 0000007559 00000 n 0000009723 00000 n Mechanism of Action. Antifungal agents that disrupt the cell membrane do so by targeting ergosterol, either by binding to the sterol, forming pores and causing the membrane to become leaky (as with polyene antifungals), or inhibiting ergosterol biosynth esis (as seen with azole antifungal agents). The molecule has a high affinity for ergosterol present in the fungal cell membrane and combines with it in such a way to make a ‘micropore. 0000010048 00000 n 0000004176 00000 n < 0000059127 00000 n 0000001944 00000 n 0000001518 00000 n https://www.webmd.com/drugs/2/drug-5115/clotrimazole-vaginal/details 0000002278 00000 n 0000003174 00000 n 0000075857 00000 n 0000001244 00000 n Antifungal agents may be classified into a number of different types, depending on their structure and the way that they work. 0000002010 00000 n 0000001423 00000 n 0000008219 00000 n trailer 0000000976 00000 n Immunosuppres- 0000011393 00000 n 0000007526 00000 n Polyene antifungals are not absorbed when given orally, so are used to treat fungal infections of the gastrointestinal tract, such as oral thrush. 0000010996 00000 n Amphotericin B (AMB) It is derived from cultures of Streptomyces Nodosus and is a very large (‘macrolide’) molecule belonging to the polyene group of antifungal agents.. Antifungal agents Fluconazole Nucotet Cap, Pharmatet Cap Aricon 50mg Cap Auro Fluconazole 150mg Cap, Mycorest 150mg Cap Diflucan 50mg/5ml Susp Griseofulvin ... Dulcolax 5mg Paed Suppository Dulcolax 10mg Suppository Lactulose Anlac Syr, Aculax Syr PEG 3350 + KCl + Na Bicarb + NaCl + NaS Klean Prep Sac, Purgolene Sac trailer 0000000016 00000 n 20 0 obj <> endobj Antifungal Agents: Mode of Action, Mechanisms of Resistance, and Correlation of These Mechanisms with Bacterial Resistance November 1999 Clinical Microbiology Reviews 12(4):501-17 0000004693 00000 n Note that only the antifungals that are available topically are listed here. 0000004083 00000 n Learn more about which product is best for you, find our latest promotions, and see how we can help with your #2. 0000006165 00000 n %PDF-1.4 %���� 0000006790 00000 n 0000001824 00000 n 557 22 0000003251 00000 n 0000000016 00000 n Antifungal agents are also called antimycotic agents. 0000002959 00000 n 0000001287 00000 n Below you can find different kinds of antifungal drugs. 0000003457 00000 n 0000004856 00000 n 0000001878 00000 n 0000000736 00000 n 0000005102 00000 n Antifungal Agents Fluconazole Difl ucan $$ Ketoconazole Oral Nizoral $$ ... Bisacodyl Dulcolax $ Docusate Calcium Surfak $ Docusate Sodium Colace $ Lactulose Cephulac/Chronulac $ ... URINARY AGENTS Oxybutynin Ditropan $$ Phenazopyridine Pyridium $$ Title: AH PDL 041118.indd Author: