Learn about the different types of sprays, how they differ, side effects, and more. 36 (£468.00/l) £9.99 £9.99 Dr. Al Hegab answered 39 … Most antihistamines can be bought from pharmacies and shops, but some are only available on prescription.They also come in several different forms – including tablets, capsules, liquids, syrups, creams, lotions, gels, eyedrops and nasal sprays.There's not much evidence to suggest any particular antihistamine is better than any other at relieving allergy symptoms.Some people find certain types work well for them and others do not. If your allergy symptoms mainly affect your nose, a nasal spray might be right for you. Products of concern include nasal decongestants (e.g., pseudoephedrine, phenylephrine, naphazoline), as found in such dosage forms as tablets, oral liquids, nasal sprays, and nasal drops. You should also avoid drinking alcohol with any antihistamine because it can increase the side effect of drowsiness.The newer second-generation and third-generation OTC oral antihistamines were developed to target their action on more specific receptors. Antihistamines are medicines often used to relieve symptoms of allergies, such as hay fever, hives, conjunctivitis and reactions to insect bites or stings. These can be used in addition to oral antihistamines to treat upper respiratory allergies (sneezing, runny nose, etc. Nasal decongestants are also popular ingredients in combination products for the common cold, allergic rhinitis, sinus problems, and flu symptoms.Some antihistamines are also hard on the prostate. But when all the recommended treatments don’t work, it might not have anything to do with the nose. Nasal sprays. Combine a powerful antihistamine and a nasal spray to tag-team allergy relief. It helps relieve runny nose, sneezing, itchy, watery eyes, and itching of the nose or throat due to hay fever and other upper respiratory allergies. Allegra can also be used to treat hives and skin rash. Benadryl also comes in topical forms, such as creams, gels, and sprays, to treat allergic skin conditions such as hives.Other common OTC brands that include the antihistamine diphenhydramine include:Chlorpheniramine is the main active ingredient in Chlor-Trimeton. Patients with renal failure or any other condition that requires them to limit fluid intake should be cautious in the use of fiber-replacement products such as psyllium (e.g., Metamucil) and methylcellulose (e.g., Citrucel).The most extensive set of warnings related to the urinary tract on any nonprescription product label is found on oxybutynin transdermal system (Oxytrol for Women).Women are advised not to use Oxytrol if they only experience accidental urine loss when they cough, sneeze, or laugh, as those are characteristic of stress incontinence, which will not be alleviated by the product. Policy 3364-133-36 2014;39(8):12-15.. They are sedating, which means they’re likely to make you drowsy after you use them. 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