Disclaimer: The information contained herein should NOT be used as a substitute for the advice of an appropriately qualified and licensed physician or other health care provider. Ten percent of individuals worldwide are affected by autoimmune diseases, with systemic lupus erythematosus (SLE) being one of the most common. Do not drive or operate heavy machinery until you know how verapamil affects you. If you are taking valacyclovir to treat cold sores, chickenpox, shingles, or genital herpes, you should start treatment as soon as possible after your symptoms start. A 34-year-old female asked: Disclaimer. They basically mean nothing and should be interpreted that way. A recent study involving high dose Zocor (80mg/day) brought out this verapamil issue along with other major concerns. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. Luckily, I found a recent meta-analysis of omeprazole that shows no increased dementia risk.Ranitidine (zantac) is the one that had a carcinogenic contaminant, not famotidine, that I can see. remdesivir) it would be very difficult to win the uphill battle (as seen e.g. I prefer the more comfortable way of living without GERD symptoms.I think that statement is too broad. same time as 2nd dose of verapamil. Making effective anti-HepC drugs took ages albeit that they had the advantage that even non drug-like big molecules could be used accumulating in the liver: fortunately the target organ for HepC virus.Finally, I wish to mention that I see several publications regarding “The Small Intestine, an Underestimated Site of SARS-CoV-2 Infection”; presumably the small intestine may get exposure of the reactive sulfenamide from PPIs.Actually, I feel repurposing drugs to suppress the cytokine storm and ARDS by Moab’s (e.g. There is doubt that the link exists, at least in that way. So with great expression of AEC2 in the gut lack of acid offers a more vulnerable target. in the mid of the pandemic if we use them as existing drugs already and are apparently safe enough: acetaminophen/paracetamol (NAPQI metabolite), omeprazole, dimethyl-fumarate, disulfiram”Omeprazole and many analogues such as Lansoprazole give active rearranged sulfenamide which act also as non-specific irreversible (disulphide formation) Cys protease inhibitor. The covalent btk inhibitor mentioned is quite selective, but perhaps very unselective and easily available omeprazole, dimethyl-fumarate and NAPQI inhibits covalently Cov-Cys proteases some endogenous btk etc etc and also works …….but of course I am looking forward to the results with the ‘forbidden’ selective covalent btk inhibitorThe Pummerer rearrangement of Omeprazole creates a pretty hot electrophile that can bind irreversibly to many structures, not only to free cysteines. If omeprazole/esomeprazole (which is readily available) are effective at increasing the efficiency of remdesivir 10 times then potentially 5 million people could take the drug till October!“If omeprazole/esomeprazole (which is readily available) are effective at increasing the efficiency of remdesivir 10 times then potentially 5 million people could take the drug till October!”Clinical studies still haven’t established a useful degree of efficacy of remdesivir in Covid 19, much less a useful (and safe) dosage regimen for SARS_CoV2 infection. Logically makes some sense to me but these are early times.I’m interested in knowing if ACE inhibitors reduce the effects of SARS-CoV2, ie. Never use this combination of drugs because of high risk for dangerous interactionPotential for serious interaction; regular monitoring by your doctor required or alternate medication may be neededPotential for significant interaction (monitoring by your doctor is likely required)Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. They say PPI meds make you 2-4 times more likely to catch COVID-19!A question put forward earlier in this blog: “why are we so afraid to give non selective irreversible Cys protease binders for 1 or 2 weeks p.o. Having some antiviral activity in the past, possibly by increasing the in... Year famotidine was pulled due to contamination with carcinogens, it did interfere with viral,. Omeprazole?????????????????... Interpreted that way be challenging.Anyone have an opinion or knowledge of this it did with... 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