This list may not describe all possible interactions. It is taken by mouth. 8 USE IN SPECIFIC POPULATIONS . Baseline corrected AUC of INR in these patients increased by 2.8-fold, and the … We comply with the HONcode standard for trustworthy health information - doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: Breast cancer that has metastasized (spread to other parts of the body) in patients whose disease has not gotten better with other chemotherapy. A clinically important XELODA-Warfarin drug interaction was demonstrated in a clinical pharmacology trial [see Warnings and Precautions (5.2) and Drug Interactions (7.1)]. Use Older adults may be more sensitive to the side effects of this medication, especially If someone has overdosed and has serious symptoms such as passing out or If you miss a dose, skip the missed dose. This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Things to remember when you fill your prescription.WebMD does not provide medical advice, diagnosis or treatment.This survey is being conducted by the WebMD marketing sciences department.All information will be used in a manner consistent with the WebMD Available for Android and iOS devices. When capecitabine is taken with leucovorin or phenytoin, for example, it can alter the levels of medication in your blood and can increase your risk of side effects. Pediatric Use 8.5 . If dehydration grade 2 or higher occurs, treatment should be interrupted until dehydration is corrected. help if any of these side effects or any other side effects bother you or do not go away: Do not store in the bathroom. These adverse reactions can be more common in patients with a prior history of coronary artery disease.Major Potential Hazard, Moderate plausibility. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Applies to: Ischemic Heart DiseaseCapecitabine can cause cardiotoxicity including myocardial infarction, ischemia, angina, dysrhythmias, cardiac failure, sudden death, electrocardiographic changes and cardiomyopathy. In patients with mild to moderate liver dysfunction due to liver metastases the Cmax and AUC of capecitabine were increased 60%. These patients should be carefully monitored when capecitabine is administered. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Capecitabine, sold under the brand name Xeloda among others, is a chemotherapy medication used to treat breast cancer, gastric cancer and colorectal cancer. Keep all Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Applies to: Fever, Bleeding, Bone Marrow Depression/Low Blood CountsCapecitabine is metabolized by the liver to fluorouracil (5-FU). Avoid tanning booths and sunlamps. taken, how much, and when it happened. The following interactions have been selected on the basis of their potential significance and are not necessarily all-inclusive.Using this medicine with any of the following medicines is not recommended. Standard antidiarrheal treatments are recommended.Moderate Potential Hazard, Moderate plausibility. All patients should be instructed to immediately report any signs or symptoms suggesting infection such as fever, sore throat, or local infection during antineoplastic therapy. CAPECITABINE (ka pe SITE a been) is a chemotherapy drug. All drugs may cause side effects. However, your doctor has prescribed this drug because he or she has judged that the benefit to you is greater than the risk of side effects. 3: This drug is available at a higher level co-pay. Discuss with your healthcare professional the use of your medicine with food, alcohol, or tobacco.The presence of other medical problems may affect the use of this medicine. Consult your Are you planning to see a doctor about switching your medication?Are you planning to see a doctor about switching your medication?Selected from data included with permission and copyrighted by First Databank, Inc. Follow all instructions closely. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Applies to: Dehydration, Diarrhea, VomitingDehydration has been observed in patients receiving capecitabine and it may cause acute renal failure which could be fatal. Avoid contact with people who have infections that may spread to others (such as To lower the chance of getting cut, bruised, or injured, use caution with sharp objects like razors and nail cutters, and avoid activities such as contact sports.This medication may make you more sensitive to the sun.