Read these instructions before using Desmopressin Acetate Nasal Spray, and each time you get a refill. increasing the dosage of Desmopressin Acetate Nasal Spray if patients
renal, or cardiac function, and of concomitant disease or drug therapyBecause elderly patients are more likely to have renal
DDAVP is contraindicated in patients with moderate to severe renal
than those listed in a Patient Information leaflet. breastmilk were obtained at 0, 30, 60, 120, 240, 360 and 480 min after the drug
If administered more than once a day, adjust for an adequate diurnal
bottle with spray pump delivering 50 sprays.Store at Controlled Room Temperature 20 to 25°C (68 to
It contains a clear, colourless solution of desmopressin acetate 0.1mg/ml. It is chemically defined as follows:1-(3-mercaptopropionic
Do not use the nasal spray in pediatric patients requiring less than 0.1 mL (10 mcg) per dose.This drug is known to be substantially excreted by the kidney, and the risk
Spray pump must be primed before you use it for the first time.This Instructions for Use has
surgery such as transsphenoidal hypophysectomy) may cause erratic, unreliable
require a reduction of the Desmopressin Acetate dosage [seeExcessive fluid intake when urine output is limited by
care should be taken in dose selection, and it may be useful to monitor renal
central diabetes insipidus in adults and pediatric patients 4 years of age and
excessive [see The recommended dosage in adults is 10 mcg once daily
insipidus during pregnancy are available; these include a few anecdotal reports
Visit the Copyright © 2020 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. relationship to drug exposure:Increase in blood pressure, headache, nasal congestion,
This information does not take the place of talking to your healthcare provider about your medical condition or treatment. information does not take the place of talking to your healthcare provider
labeling (Studies with desmopressin acetate have not been performed
for patients who require less than 10 mcg doses or doses that are not multiples
should be observed for the following signs or symptoms associated with
absorbed through the nasal mucosa.Desmopressin acetate exhibits a
with passing DDAVP is contraindicated in patients with moderate to severe If you accidentally deliver/administer too much of a dose, immediately telephone your doctor or a certified Regional Poison Center for advice. Desmopressin Acetate Nasal
acid)-8-D-arginine vasopressin monoacetate (salt) trihydrate.Desmopressin Acetate Nasal
Possible signs of overdose may include confusion, drowsiness, continuing headache, problems with passing urine and rapid weight gain due to fluid retention.Store at Controlled Room Temperature 20 to 25°C (68 to 77°F) [see USP]. The terminal half-life was 2.8 hours in subjects with
Some patients may show a decreased responsiveness, others a shortened duration of effect. diabetes insipidus.Tell your healthcare provider about all the medicines you
of 10 mcg because the spray pump can only deliver doses of 10 mcg [see Individualize the dosage of Desmopressin Acetate Nasal
oxybutynin and carbamazepine) requires more frequent serum sodium monitoring [see
patients requires careful fluid intake restriction to prevent possible water
function. elsewhere in the labeling:The following adverse reactions have been identified
initial and terminal phases, respectively.Desmopressin acetate is mainly excreted in the urine. To prime, press down 4 times.