Switching Between Desmopressin Acetate Formulations. ddavp-stimate-noctiva-desmopressin-342819
doi: 10.1371/journal.pone.0216770. Medscape prescription drug monographs are based on FDA-approved labeling information, unless otherwise noted, combined with additional data derived from primary medical literature. conversion from intravenous (IV) to oral (PO) formulations of the same medication while maintaining equivalent potency is known as “sequential therapy”.
2014 Apr;5(2):83-7. doi: 10.4103/0976-500X.130042.Mayo Clin Proc. Nasal Spray: 10-40 mcg daily (or divided 2-3 times per day) Intranasal 5 mcg equivalent to 0.1 mg oral; Oral Tablet: 0.05 to 1.2 mg orally daily (or divided 2-3 times daily) Subcutaneous or IV: 2-4 mcg/day IV/SC divided twice daily; VIII.
Epub 2016 Feb 22.PLoS One.
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Repeat administration should be determined by laboratory response as well as the clinical condition of the patient.IV: 0.3 mcg/kg once slowly over 15-30 minutes.
2002
This conversion has many advantages as fewer complications, less healthcare costs and earlier hospital discharge.
Forty percent of patients on nasal desmopressin experienced hypo/hypernatraemia compared to 18.1% on oral, however, there were no significance difference between standardized hypo/hypernatraemia episodes per treatment year.
Preoperative IV doses may be given 30 minutes prior to scheduled procedure. and formulary information changes. Please enable it to take advantage of the complete set of features! We comply with the HONcode standard for trustworthy health information - encoded search term (desmopressin (DDAVP%2C Stimate)) and desmopressin (DDAVP, Stimate) Society of Cardiovascular Anesthesiologists Clinical Practice Improvement Advisory for Management of Perioperative Bleeding and Hemostasis in Cardiac Surgery PatientsLate Dinner Affects Metabolism, May Lead to Weight Gain, DiabetesMetabolic Disease: Is It the Fat, Sugar, or Processed Food?
ddavp.
Drugs
Please enable it to take advantage of the complete set of features! 2012 Sep;67(9):2289-96. doi: 10.1093/jac/dks193.
Diseases & Conditions
2010
Hospitalized patients initially on intravenous antibiotics can be safely switched to an oral equivalent within the third day of admission once clinical stability is established. IV: 0.3 mcg/kg by slow infusion over 15 to 30 minutes beginning 30 minutes before procedure. Excluded were patients admitted to care or surgery units, or those with gastrointestinal diseases, infections that require prolonged course of parenteral therapy, or malignancies. Epub 2018 Jun 17.Dryden M, Saeed K, Townsend R, Winnard C, Bourne S, Parker N, Coia J, Jones B, Lawson W, Wade P, Howard P, Marshall S.J Antimicrob Chemother.
Sheridan PubFactory
The three types of intravenous to oral conversion include sequential, switch, and step-down therapy. Springer
The study showed that among 452 intravenous antibiotic courses from 356 patients who were eligible for conversion, only one third were switched and the others continued on intravenous antibiotics beyond day 3 (P <0.0001).
Adult inpatients on intravenous antibiotics for 2 days and more were eligible for study enrollment.
Unable to load your delegates due to an error 2020 Jan 30;15(1):e0227736.
Supplied: 4 mcg/ml-1 ml vial..
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