Until now, my period stop completely about 4 months and I started immediately with anxiety ( wish I thought it was produced by a very stressful job and a traumatic eclampsia experience by my daughter with her first baby just at the same months that I loose my period) sleep deprivation and hot flashes. No fetal developmental anomalies were observed. DESCRIPTION. If you would like more information, talk with your healthcare In vitro data suggest that bazedoxifene is unlikely to interact with co-administered drugs via CYP-mediated Bazedoxifene undergoes metabolism by UGT enzymes in the intestinal tract and liver. You may report side effects to FDA at 1-800-FDA-1088.Ask your healthcare provider for ways to lower your I definitely do not want another bladder infection and am wondering if I can do the Premsrin cream for another month while I give the Duavee a try. It's daunting to read all the studies and possibility of uterine cancer and breast and so forth. Never delay or disregard seeking professional medical advice from your doctor or other qualified healthcare provider because of something you have read on WebMD. Hi, I am new to Duavee. Glucuronidation is the major metabolic pathway. Thanks for the info. 4 days into Duavee I am having a period. My main concern is my sex drive and I told my dr. that. I haven't had a period in 3 years just annoying hot flashes And dryness vaginally and I'm also on Effexor for anxiety and small amount of lisinipril for hypertension and borderline cholesterol family has it. But did my homework on CEE (the estrogen in Duavee) and BZA (the other part). WebMD understands that reading individual, real-life experiences can be a helpful resource but it is never a substitute for professional medical advice, diagnosis, or treatment from a qualified health care provider. Reviewer: Deb, 55-64 on Treatment for 1 to less than 2 years (Patient) 0 23 reviews submitted with a 6.7 average score. Low-grade stage zero tumor removal a year ago. Women enrolled in Studies 1 and 2 received calcium (600- 1200 mg) and vitamin D (200-400 IU) daily, while women in Studies 3 and 4 received no calcium and vitamin D supplementation as part of the protocol.The incidence of all-cause mortality was 0.0% in the DUAVEE group and 0.2% in the placebo group. Common side effects of Duavee … I've been doing some reading on the latest research on Duavee, and it still looks great to me (and I'm still using it). I found a doc 5 days ago who put me immediately in Duevee, OMG game changing!! I have yearly breastfeeding screenings, pap tests, and a yearly uterine biopsy. Has anyone found a solution? p.s. This reduction can occur at any time but is less likely to occur once breast-feeding is well-established.There are no data on the presence of bazedoxifene in either human or animal breast milk, the effect on the breastfed infant, or the effects on milk production. I only use 1 gram once a week of the Estrace for vaginal dryness. Lost 12 pounds. The Cmax and AUC of unconjugated estrone increased by 11% and 3%, respectively. I don't believe the sleep issues are from hot flashes - they have never been a problem. Has anyone been on an estrogen patch and taken raloxifene with it? I cant wrap my head around that one :) PS-Im 51 and have been on long cycle HRT for about 2 years and just switched to Duavee due to progest intolerance. Also, taking estrogen orally can cause your liver to increase sex hormone binding globulin (SHBG) which is a carrier protein that makes hormones unavailable to your cellular receptors when hormones are bound to the protein. I felt like an old lady and wanted to crawl under a rock somewhere and just die. Any idea why they combined the great bazedoxifine with a conjugated estrogen made from pregnant mare urine, rather than estradiol? Each tablet of DUAVEE contains the following inactive ingredients: calcium phosphate tribasic, hydroxypropyl cellulose, microcrystalline cellulose, powdered cellulose, hypromellose, lactose monohydrate, magnesium stearate, polyethylene glycol, sucrose, ascorbic acid, sucrose palmitic acid ester, hydroxyethylcellulose, titanium dioxide, red iron oxide, yellow iron oxide, black iron oxide, povidone, polydextrose, maltitol, poloxamer 188, propylene glycol, and isopropyl alcohol.Take DUAVEE once daily, without regard to meals.