Please check with a physician if you have health questions or concerns. Although many transplant facilities are exploring the use of either calcineurin or steroid minimization/withdrawal protocols, to date there is no single-agent regimen that successfully prevents organ rejection in all transplant populations.Fungal infections are estimated to occur in 5% of kidney transplant recipients and up to 40% of liver recipients.Bacterial infections are among the leading complications occurring posttransplant.Hypertension is a common comorbidity affecting a large proportion of transplant patients. These medicines include immunosuppressants to prevent organ rejection, prophylactic anti-infectives, stress ulcer prophylaxis, and other maintenance medications for underlying chronic diseases. Common antiepileptic drugs?such as phenytoin, carbamazepine, and phenobarbital?are known strong inducers of the CYP450 system. It usually starts to work within one day, but it may take 3 days for your symptoms to improve and up to 7 days for your symptoms to disappear. There are, however, a few ways for patients to reduce their risk for potential drug interactions. Public Citizen has published a list of 56 drugs that interact badly with erectile dysfunction pills such as Pfizer's Viagra. Potential Drug Interactions ... fluoxetine, fluvoxamine, fluconazole, and voriconazole. Nefazodone, a mixed SSRI and norepinephrine reuptake inhibitor, is a potent CYP3A4 inhibitor and should be avoided in transplant patients due to the potential for severe toxicity. Although we attempt to provide accurate and up-to-date information, no guarantee is made to that effect. Venlafaxine has mild interactions with at least 65 different drugs. It is also used to treat nausea and spinning sensations (vertigo) due to Ménière's disease and other conditions that cause … Effexor and Antidepressants. Pill Identifier Tool Quick, Easy, Pill Identification. Of the many different approved antihypertensives, only calcium channel blockers complicate immunosuppressive management. Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. This tool may not cover all possible drug interactions. These can cause serious side effects such as vomiting, seizures, collapse, and coma. This eMedTV page contains a list of medications that may cause drug interactions with colestipol, such as propranolol, ursodiol, and digoxin. The latter condition is ultimately fatal if not treated. Numerous case reports cite interactions between calcineurin inhibitors and St. John's wort, a popular herbal used for the treatment of depression.Other herbals with immune-stimulating effects?such as echinacea, astragalus, ginseng, licorice, and alfalfa sprouts?should be avoided.A variety of other medications are known to interact with transplant immunosuppressants. Most selective serotonin reuptake inhibitors (SSRIs)? Nondihydropyridine calcium channel blockers (verapamil, diltiazem) are well-known inhibitors of immunosuppressant metabolism. Some of the more problematic interactions occur with antiseizure or antiretroviral medications. Please check with a physician if you have health questions or concerns. Other antidepressants?such as venlafaxine, bupropion, mirtazapine, tricyclics, and monoamine oxidase inhibitors?are not recommended as first-line agents because of problematic side effects.Grapefruit juice, a staple in many Americans' diets, is a known inhibitor of CYP3A4. Fluconazole: Fluconazole 150 mg capsules are an antifungal medication used to treat vaginal yeast infections caused by the yeast known as Candida. Transplantation affords patients the opportunity for a more normal life. Drug interactions with food and beverages. Sertraline and escitalopram are considered the antidepressants of choice because of their minimal drug interactions and side effects. Patients should use one pharmacy so as to keep accurate records of all prescription medications; they should inform all physicians of current prescription, OTC, supplement, or herbal usage; and they should take an active part in learning about the warnings for the medications they consume.Expert panelists review the causes, diagnostic work-up, management, and emerging therapies inherent in the evolving paradigm of irritable bowel syndrome.Transplant Immunosuppressants: Common Drug InteractionsTransplant Immunosuppressants: Common Drug Interactions2 Clarke Drive Suite 100 Cranbury, NJ 08512 P:609-716-7777 F:609-716-9038