Read all of the instructions carefully before using this pen. Vasospastic coronary artery disease. Sumatriptan Succinate Injection is contraindicated in patients with a history of hypersensitivity reaction to sumatriptan.The needle shield of the prefilled syringe contains dry natural rubber (a latex derivative) that has the potential to cause allergic reactions in latex-sensitive individuals.Seizures have been reported following administration of sumatriptan. History, symptoms, or signs of ischemic cardiac (eg, MI, angina pectoris, silent myocardial ischemia), cerebrovascular (eg, stroke, TIA), or peripheral vascular (eg, ischemic bowel disease) syndromes. To create this article, 10 people, some anonymous, worked to edit and improve it over time. If you have these symptoms, do not drive a car, use machinery, or do anything where you need to be alert.The most common side effects of Sumatriptan Succinate Injection include:Tell your healthcare provider if you have any side effect that bothers you or that does not go away.These are not all the possible side effects of Sumatriptan Succinate. You can ask your healthcare provider or pharmacist for information about Sumatriptan Succinate that is written for healthcare professionals.For more information, go to www.gsk.com or call 1-888-825-5249.Inactive ingredients: sodium chloride, water for injectionBrands listed are trademarks of their respective owners.This Patient Information has been approved by the U.S. Food and Drug Administration. This article has been viewed 8,888 times. These trials did not establish the efficacy of oral sumatriptan compared with placebo in the treatment of migraine in pediatric patients. The highest no-effect dose for this finding was 100 mg/kg/day.Sumatriptan is excreted in human milk following subcutaneous administration The developmental and health benefits of breastfeeding should be considered along with the mother’s clinical need for Sumatriptan Injection and any potential adverse effects on the breastfed infant from sumatriptan or from the underlying maternal condition.Infant exposure to sumatriptan can be minimized by avoiding breastfeeding for 12 hours after treatment with Sumatriptan Succinate Injection.Following subcutaneous administration of a 6-mg dose of Sumatriptan Injection in 5 lactating volunteers, sumatriptan was present in milk.Safety and effectiveness in pediatric patients have not been established. • There are reports, albeit very rare, of true angina, heart attack, heart arrhythmia, or stroke as possible complications of sumatriptan use. The highest no-effect dose for this effect was 60 mg/kg/day. Other reported clinical experience has not identified differences in responses between the elderly and younger patients. This medicine also reduces substances in the body that can trigger headache pain, nausea, sensitivity to light and sound, and other migraine symptoms. Medication overuse headache may present as migraine‑like daily headaches, or as a marked increase in frequency of migraine attacks. To create this article, 10 people, some anonymous, worked to edit and improve it over time. Written instructions and accompanying photographs dealing with self-administration of sumatriptan are available at most pharmacies and are enclosed in the self-dosing kit you will receive with your initial prescription. There were insufficient data to assess the impact of race on the incidence of adverse reactions.In the controlled clinical trials assessing the efficacy of Sumatriptan Succinate Injection as a treatment for cluster headache (Studies 4 and 5), no new significant adverse reactions were detected that had not already been identified in trials of sumatriptan succinate in patients with migraine.Overall, the frequency of adverse reactions reported in the trials of cluster headache was generally lower than in the migraine trials. Do not give Sumatriptan Succinate to other people, even if they have the same symptoms you have. Headache relief, as defined by a reduction in pain from severe or moderately severe to mild or no headache, was achieved in 70% of the patients within 1 hour of a single 6-mg subcutaneous dose of Sumatriptan Succinate Injection. Visually inspect device prior to administration. In patients who experience symptoms or signs suggestive of non-coronary vasospasm reaction following the use of any 5‑HTReports of transient and permanent blindness and significant partial vision loss have been reported with the use of 5‑HTOveruse of acute migraine drugs (e.g., ergotamine, triptans, opioids, or combination of these drugs for 10 or more days per month) may lead to exacerbation of headache (medication overuse headache). The pH range of both solutions is approximately 4.2 to 5.3. There may be new information. If you really can’t stand to see another ad again, then please We use cookies to make wikiHow great.