However, these studies give us a sense for how well a patient can expect to do if she has irregular, or non-existent, cycles and is using a gonadotropin-plus-IUI approach.The good news is that the pregnancy rate is favorable: 20 - 26% per cycle compared with the study above that showed clomid-plus IUI-was ~19% across The bad news is that gonadotropins produce a high multiple pregnancy rate, especially in this population. It’s also worth noting that PCOS patients who are taking gonadotropins have a very high risk of multiples.When PCOS patients who don’t ovulate, or irregularly ovulate, must choose between taking clomid or letrozole, without IUI, the data typically favors letrozole. Therefore, most doctors prefer prescribing vaginal suppositories or tablets after IUI.Progesterone given by intramuscular injections tends to be very effective as well.However, progesterone taken may not be as effective as vaginal application methods.Most women may like to know when to start progesterone after IUI. David H. Barad, MD, MS, is an expert reproductive endocrinologist with decades of experience in treating women with aging ovaries and patients with multiple failed IVF cycles. You should NOT sign the consent form(s) until you meet with your nurse coordinator to go over the consent forms. For this reason, many clinics have moved away from using gonadotropins in IUI cycles. The procedure itself involves transferring semen that has been washed in a special way directly into the uterus via a thin catheter. The information on this website is of a general nature and available for educational purposes only and should not be construed as a substitute for advice from a medical professional or health care provider. Some of these include adding medications such as dexamethasone or metformin to the treatment regimen. Your use of this site indicates your agreement to be bound by the Terms of Use. This likely means that for the women who haven’t become pregnant by that point, there is likely another factor that is making it difficult to achieve pregnancy and IVF probably should be considered.As we alluded to in the second lesson, all things being equal, IUI success rates are higher with fresh sperm than with frozen and thawed sperm. In case your body is making enough, you may not require supplements. It has a very few associated risks. Patients most susceptible are often under 35 years old or have PCOSWhile IUI success rates are lower than with IVF (2 -10x), so are costs (5 - 40x) and in early IUI cycles, cost-per-live-birth can be lower than in IVF. An account with this email address already exists in The CHR portal. Epub 2013 Jul 19.Montville CP, Khabbaz M, Aubuchon M, Williams DB, Thomas MA.Fertil Steril. By contrast, when these patients do IUI with just clomid, the percentage of pregnancies that resulted in twins was 9%.In PCOS patients, IUI cycles that include gonadotropins can take a long time (sometimes 3 or 4 weeks). When you are unsure about something along the way, you can always come back to this page to refresh your memory.A series of tests are required before an IUI cycle can take place, on both female and male partners. 2010 Jul;94(2):678-83. doi: 10.1016/j.fertnstert.2009.03.088. Should you have any concerns about your health, or of that of your baby or child, please consult with your doctor.
Once you and your physician determine the type of treatment for you, you will receive a packet of informed consent forms from your clinical coordinator. The success rates of IUI are 10% – 30%. In some instances, women have also reported a negative response to the carrier which contained the progesterone.Taking progesterone after IUI is essential, as it helps strengthen the uterine lining, making it favourable for implantation of the embryo.
I did 5 IUI's with a previous RE and with all of them, she had me take progesterone after the IUI. A higher dose often means more eggs ovulated and a greater risk of twins or more.The take home message of these studies is that when gonadotropins are given to this patient population at a dose that doesn’t put the patient at significant risk of twins (like the 75 units in the Huang study), they are no better than oral medications (clomid and letrozole) at producing successful pregnancies. For these patients, Next we have patients who have either PCOS or no diagnosis. I had an IUI today with a new RE and surprisingly, she did not prescribe progesterone for me. In these patients, the goal of an IUI cycle is to have 2 or 3 eggs ovulated in a given cycle (rather than the typical one egg per cycle) to increase the chance of pregnancy. Progesterone supplements are a form of natural progesterone used after an intrauterine insemination (IUI) to help promote pregnancy. 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