After switching to formula feeding and no further infant exposure to penicillins, the reaction did not reappear with follow-up to 16 months of age. [PubMedFrenkel LM, Brown ZA, Bryson YJ et al. Topical acyclovir applied to small areas of the mother's body away from the breast should pose no risk to the infant. Of 40 infants exposed to amoxicillin in breastmilk, 2 developed diarrhea and 1 developed a rash. [5]A study compared the breastfed infants of mothers taking amoxicillin to those taking a macrolide antibiotic. Regul Toxicol Pharmacol. [PubMedGoldstein LH, Berlin M, Tsur L et al. See below. DisperMox, Wymox, Biomox, Amoxicot, Moxilin, AmoclanWe comply with the HONcode standard for trustworthy health information - Prospective follow-up of adverse reactions in breast-fed infants exposed to maternal medication. 1994;28:585-7. [PubMedCampbell AC, McElnay JC, Passmore CM. 2009;23 (Suppl 1):37. 2009;4:197-200. The authors estimated that a fully breastfed infant would receive a daily dosage of 0.73 mg/kg of acyclovir at this maternal dosage or about 1% of the maternal weight-adjusted dosage. The drug that caused the reaction cannot be determined, but it was most likely the amoxicillin/clavulanic acid. Select one or more newsletters to continue. Weight change and the development of jaundice were also recorded. Introduction to the Safety of Drugs passing through Breastmilk FAQs on Breastfeeding and Medication Patient Information Leaflets – what do they mean? 2005;27:499-502. [PubMedTaddio A, Klein J, Koren G. Acyclovir excretion in human breast milk. Three milk acyclovir levels on days 5 and 6 of therapy ranged from 4.2 to 5.8 mg/L, with the highest level 9.4 hours after the previous dose. Available for Android and iOS devices.Noti A, Grob K, Biedermann M et al. Occasionally, rash and disruption of the infant's gastrointestinal flora, resulting in diarrhea or thrush, have been reported, but these effects have not been adequately evaluated. Dosages received in breastmilk with high maternal doses are only about 3 to 5% of this dose. [PubMedKafetzis DA, Siafas CA, Georgakopoulos PA et al. Acyclovir in human breast milk. 1981;70:285-8. 1991;164:569-76. Ther Drug Monit. The excretion of ampicillin in breast milk and its effect on the suckling infant. Breastfeed Med. I asked her if it was O.K to take while nursing and she said something along the lines of,"yes, it's perfectly safe. [5]Relevant published information was not found as of the revision date.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Gavreto (pralsetinib) is an oral selective RET kinase inhibitor for the...Onureg (azacitidine) is a nucleoside metabolic inhibitor indicated for the...Qdolo (tramadol hydrochloride) is an opioid agonist indicated in adults for ...Xaracoll (bupivacaine hydrochloride) is a fully bioresorbable collagen implant...The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Kellymom.com has a partial list of drugs approved by the AAP for use during lactation. [PubMedBork K, Benes P. Concentration and kinetic studies of intravenous acyclovir in serum and breast milk of a patient with eczema herpeticum. Select one or more newsletters to continue. Arch Dis Child. [6]A 2-month-old infant breastfed since birth. [4]A prospective, controlled study asked mothers who called an information service about adverse reactions experienced by their breastfed infants. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products.