You must declare any conflicts of interest related to your comments and responses. Patients in a university headache clinic completed a survey regarding their experience with memantine, and medical records were reviewed. Some features of the site may not work correctly.The objective was to retrospectively characterise the efficacy of memantine as preventive therapy in a series of patients with frequent migraine. Memantine reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer's disease.. Memantine is used to treat moderate to severe dementia of the Alzheimer's type.. Memantine may also be used for purposes not listed in this medication guide. To comment please Comments on Medscape are moderated and should be professional in tone and on topic. Methods: This clinical trial was conducted over a period of 3 months. On the 5th day the headaches stopped, but she became nauseous and woozy. Two preventative studies of memantine for migraine have been published—both showed promising results. Patients were treated with memantine beginning at a dose of 5 mg… Memantine in the preventive treatment of refractory migraine.Memantine for Prophylactic Treatment of Migraine Without Aura: A Randomized Double-Blind Placebo-Controlled Study.Sports Concussion and the Clinical Neurologist, Part II Neurologists, who increasingly will confront patients diagnosed with sports concussion, must be adept at identifying and managing the condition. You must declare any conflicts of interest related to your comments and responses. If you log out, you will be required to enter your username and password the next time you visit. 36 out of 54 treated with memantine for at least two months reported a significant reduction in estimated headache frequency, and improved function. Noruzzadeh, Amirhossein Modabbernia, … Abbas TafakhoriBy clicking accept or continuing to use the site, you agree to the terms outlined in our She continues to be headache free, but feels awful. Nicolodi M(1), Galeotti N, Ghelardini C, Bartolini A, Sicuteri F. Author information: (1)Interuniversity Center, Neurochemistry and Clinical Pharmacology of Idiopathic Headache, Viale G. Pieraccini 18, 1-50139, Florence, Italy. Please see our Comments on Medscape are moderated and should be professional in tone and on topic. You are currently offline. Objective: To assess the efficacy of Memantine as a preventive and therapeutic intervention for migraine and tension-type headache. Anand Shanmugam, Kranthi Karunaikadal, … Muthuraj KrishnanR. Patients in a university headache clinic completed a survey regarding their experience with memantine, and medical records were reviewed. All material on this website is protected by copyright, Copyright © 1994-2020 by WebMD LLC. 2002 Jul-Aug;42(7):596-602. The objective was to retrospectively characterise the efficacy of memantine as preventive therapy in a series of patients with frequent migraine. Secondary headaches are caused by an underlying disorder, whereas primary headaches are themselves the disorder. Please see our Headaches are one of the most common afflictions encountered in clinics today.In the United States alone, nearly 30 million people suffer from migraines, and the numbers are on the rise.Click the topic below to receive emails when new articles are available. She took 5mg nightly for 4 days and during that time she had a headache every day. All patients who received memantine as preventive therapy for migraine over a 15-month period were mailed surveys and consent forms for record review. Part II of a series reviews screening modalities.„Dopalacze” – eksperyment wysokiego ryzyka, w ujęciu przepisów nowej ustawyMemantine for Prophylaxis of Chronic Tension-Type Headache—A Double-Blind, Randomized, Crossover Clinical TrialMemantine for Prophylactic Treatment of Migraine Without Aura: A Randomized Double-Blind Placebo-Controlled Study.Tolerability and Efficacy of Memantine as Add on Therapy in Patients with MigraineAches and Trauma : Understanding Post-Traumatic Headache , Part 2 : Management and TreatmentTreatment of patients comorbid with alcohol dependence and major depressive disorder with memantine and escitalopram - outcome and predictorsMemantine for the prophylaxis of chronic tension-type headacheTherapeuticpotentialofnovel glutamatereceptorantagonists inmigraineInsights into the pharmacological targeting of the trigeminocervical complex in the context of treatments of migraineMemantine in severe dementia: results of the 9M-Best Study (Benefit and efficacy in severely demented patients during treatment with memantine).The chemical biology of clinically tolerated NMDA receptor antagonists.Comments on “Memantine Blocks α7* Nicotinic Acetylcholine Receptors More Potently Than N-Methyl-d-aspartate Receptors in Rat Hippocampal Neurons”Effects of Pan- and Subtype-Selective N-Methyl-d-aspartate Receptor Antagonists on Cortical Spreading Depression in the Rat: Therapeutic Potential for MigraineMemantine blocks alpha7* nicotinic acetylcholine receptors more potently than n-methyl-D-aspartate receptors in rat hippocampal neurons.Memantine Blocks α7* Nicotinic Acetylcholine Receptors More Potently Than N-Methyl-D-aspartate Receptors in Rat Hippocampal NeuronsOpen-channel block of N-methyl-D-aspartate (NMDA) responses by memantine: therapeutic advantage against NMDA receptor-mediated neurotoxicityThe N-methyl-d-aspartate receptor channel blockers memantine, MRZ 2/579 and other amino-alkyl-cyclohexanes antagonise 5-HT3 receptor currents in cultured HEK-293 and N1E-115 cell systems in a non-competitive mannerEffects of pan-and subtype-selective NMDA receptor antagonists on cortical spreading depression in the rat : therapeutic potential for migraineS.