Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Cough 4. Dizzy 6. All rights reserved. Learn about side effects, warnings, dosage, and more. Head Pain Namenda XR (memantine)." In particular, memantine blocks excessive NMD… These side effects may go away during treatment as your body adjusts to the medicine. Although not all of these side effects may occur, if they do occur they may need medical attention.Some side effects of memantine may occur that usually Check with your health care professional if any of the following side effects The most common adverse reactions (frequency of at least 5% and higher than placebo) were dizziness, headache, confusion, constipation, and diarrhea.1. This antagonist, which has fewer side effects than other NMDA antagonists, is believed to work by competing with magnesium in the synapse, which inhibits the prolonged influx of calcium. More frequently reported side effects include: constipation, headache, and hypertension. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Available for Android and iOS devices.We comply with the HONcode standard for trustworthy health information - If one considers that there might be a commonality or overlap of signal barrage to the spinal cord or brainstem in chronic pain and chronic headache states, the glutamate system might be a point of amplification or reinforcement of the pain transmission cascade in these clinical conditions. Common side effects of Namenda include: tiredness, body aches, joint pain, dizziness, nausea, vomiting, diarrhea, constipation, loss of appetite, weight loss, headache, swelling in your hands or feet, We wanted to explore the efficacy of blockade of NMDA receptors in the treatment of migraines and chronic tension-type headaches using a low-affinity antagonist, memantine. Although not all of these side effects may occur, if they do occur they may need medical attention.Check with your doctor immediately if any of the following side effects occur:Some side effects may occur that usually do not need medical attention. 3. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. O 02. memantine showed low to negligible affinity for GABA, benzodiazepine, dopamine, adrenergic, histamine and glycine receptors and for voltage-dependent Ca 2+, Na + or K + channels. All rights reserved. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Other side effects not listed may also occur in some patients. Along with its needed effects, memantine may cause some unwanted effects. O 0Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Some side effects may not be reported. Namenda (memantine)." "Product Information. Cerner Multum, Inc. "Australian Product Information." You may report side effects to the FDA at 1-800-FDA-1088.Portions of this document last updated: Feb. 01, 2020Copyright © 2020 IBM Watson Health. Constipation 3. Memantine oral tablet is a prescription medication used to treat moderate to severe dementia caused by Alzheimer’s disease. See below for a comprehensive list of adverse effects. Namenda (memantine hydrochloride) is an orally active NMDA receptor antagonist used to treat moderate to severe Alzheimer's type dementia. You may report them to the The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Forest Pharmaceuticals, St. Louis, MO. Less common Anxiety back pain bladder pain bloody or cloudy urine change in walking and balance chills clumsiness or unsteadiness cough producing mucus coughing diarrhea difficult, burning, or painful urination difficulty with breathing difficulty … Diarrhea 5. Postmarketing side effects of memantine reported include: Blood and lymphatic system disorders: vulnerability to infection ( agranulocytosis ); reduced white blood cells ( leukopenia , neutropenia ); deficiency of red blood cells , white blood cells and platelets ( pancytopenia ); low platelets ( thrombocytopenia ); blood clots ( thrombotic thrombocytopenic purpura [ TTP ]) If you notice any other effects, check with your healthcare professional.Call your doctor for medical advice about side effects. Our general interest e-newsletter keeps you up to date on a wide variety of health topics.Along with its needed effects, a medicine may cause some unwanted effects. Confused 2. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. "Product Information. Forest Pharmaceuticals, St. Louis, MO. If experienced, these tend to have a Less Severe expression 1. Cerner Multum, Inc. "UK Summary of Product Characteristics." 4. 9,12 This inhibition blocks neuronal excitation or CSD and therefore is thought to inhibit migraine pain.