Hence, if an individual consumes a high amount of alcohol and has to take the drug, it is recommended that he or she talks to a doctor first.To conclude, understand that metronidazole when consumed with alcohol may not always lead to the above side effects or health consequences. The side effects of this combination are: Nausea; Flushing of skin 296.54Disulfiram, USP occurs as a white to off-white, odorless, and almost tasteless powder, soluble in water to the extent of about 20 mg in 100 mL, and in alcohol to the extent of about 3.8 g in 100 mL.Each tablet for oral administration contains 250 mg or 500 mg Disulfiram, USP. This category only includes cookies that ensures basic functionalities and security features of the website. This effect can happen if alcohol is consumed shortly before starting the antibiotic, during the course of the antibiotic, and up to a few days after taking the antibiotic. However, it is possible that disulfiram-like reaction can occur in some subgroups and by other mechanisms than the inhibition of hepatic ALDH. Patients treated with metroNIDAZOLE topical should avoid using any products containing alcohol or propylene glycol during and for up to 3 days until after completion of therapy. Select one or more newsletters to continue. With common antibiotics, this combination may not cause any problems; however, with certain medication, it is likely to cause serious complications. These cookies will be stored in your browser only with your consent. We offer the latest information for being the best, most healthy “you” you can be, covering areas ranging from nutrition and exercise to sleep and stress management.This website uses cookies to improve your experience while you navigate through the website. Occasionally, mixing metronidazole with alcohol may trigger reactions resembling signs of disulfiram reaction because alcohol interferes with the ability of the liver to metabolize metronidazole. 4.3 Interaction with Alcohol. Discontinue alcohol consumption during and … Consumption of alcoholic beverages or products containing alcohol or propylene glycol during treatment with metroNIDAZOLE topical may occasionally trigger a reaction in some patients similar to the disulfiram reaction, which includes unpleasant effects such as flushing, throbbing in head and neck, throbbing headache, difficulty breathing, nausea, vomiting, sweating, thirst, chest pain, rapid heartbeat, … Manufacturer advises avoid for at least 48 hours stopping treatment. Disulfiram, USP is an alcohol antagonist drug.CHEMICAL NAMEbis(diethylthiocarbamoyl) disulfide.STRUCTURAL FORMULAC10H20N2S4 M.W. One such medication is metronidazole. Rarely, more severe reactions may include abnormal heart rhythm, heart attack, heart failure, unconsciousness, convulsions, and even death. In case you have suffered or are suffering from these following problems after the consumption of the two, please consult a doctor.Needless to say, alcoholism and metronidazole do not go well together. We also use third-party cookies that help us analyze and understand how you use this website. Alcohol (beverage) potentially causes a disulfiram-like reaction when given with metronidazole. You also have the option to opt-out of these cookies. We comply with the HONcode standard for trustworthy health information - It is important to tell your doctor about all other medications you use, including vitamins and herbs. Well, we're looking for good writers who want to spread the word. Yet, even if it has not been very specifically proved, it is good to stay away from consuming this duo together. Do not stop using any medications without first talking to your doctor.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Tablets also contain colloidal silicon dioxide, lactose anhydrous, magnesiu… Alcohol mixed with metronidazole can have a VERY unpleasant side effect: violent vomiting (for more information on this, google "disulfiram reaction"). The article below elaborates on the effects of the interaction between alcohol and metronizadole.Alcohol is an intoxicating drink and apart from the expected health problems, it is likely to cause more damage when consumed along with medication. This study shows that metronidazole does not have an effect on blood acetaldehyde concentrations when ingested with ethanol and does not have any objective or subjective disulfiram-like properties. 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