This medication is available … Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. This medicine is not for long-term use. This product is available in the following dosage forms:Portions of this document last updated: Feb. 01, 2020Copyright © 2020 IBM Watson Health. Squeeze enough ointment from the tube to coat a cotton swab (about ½ ounce). Put the swab into one nostril and gently move it around the lower part of the nostril in a circular motion. This can help prevent the growth of staph bacteria in patients with a high risk of infection.Mupirocin nasal may also be used for purposes not listed in this medication guide.Follow all directions on your medicine label and package. If your nasal swab is positive for S. aureus, treatment with Bactroban for 5 days before surgery has been shown to decrease surgical site infections by 69%. Background: Mupirocin is a natural antibiotic from Pseudomonas fluorescens which is available as a 2% ointment. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.If you miss a dose of this medicine, take it as soon as possible. It is used to eliminate staphylococcal bacteria from the nasal passages. This medicine is available only with your doctor's prescription. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. 2010 Dec;58(12):657-9. doi: 10.1007/s11748-009-0582-2. This is an antibacterial medicine. Epub 2005 Dec 27.Ramirez MC, Marchessault M, Govednik-Horny C, Jupiter D, Papaconstantinou HT.J Gastrointest Surg. Wash your hands before and after use. You may report side effects to FDA at 1-800-FDA-1088.Topical cream: Apply a small amount to the affected area 3 times a day for 10 days.Nasal ointment: Apply about one-half of the tube contents into 1 nostril and the other half into the other nostril twice a day (morning and evening).Topical ointment: Apply a small amount to the affected area 3 times a day.Medicine used in the nose is not likely to be affected by other drugs you use. Epub 2008 Apr 2.Perl TM, Cullen JJ, Wenzel RP, Zimmerman MB, Pfaller MA, Sheppard D, Twombley J, French PP, Herwaldt LA; Mupirocin And The Risk Of Staphylococcus Aureus Study Team.N Engl J Med. Do not double doses.Do not keep outdated medicine or medicine no longer needed.Ask your healthcare professional how you should dispose of any medicine you do not use.Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). The dose of this medicine will be different for different patients. For single use nose ointment, place 1/2 the ointment from the tube into one nostril and the other 1/2 into the other nostril. Use one half of the medicine from a single-use tube in each nostril, then throw the tube away. Clin Infect Dis. Use the medicine exactly as directed.Do not take by mouth. Do not miss any doses. For reducing infections after hip and knee replacement, the answer appears to be yes. Follow your doctor's orders or the directions on the label. 2013 Jan;17(1):144-52; discussion p.152. 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