Patients on these should be closely monitored for lack of effectiveness, and a Nimodipine dosage increase may be required. It is a calcium channel blocker of the dihydropyridine type. Accidental injection of nimodipine can cause serious (rarely fatal) side effects (such as low blood pressure, slow heartbeat). Learn about side effects, warnings, dosage, and more. Baroreflex desensitization may occur when short-acting nifedipine tablets are given over the long term, with a decrease of the adrenergic-mediated reflexes. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Keep each capsule in the original package until you are ready to take one.Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Nimodipine was embryotoxic, causing resorption and stunted growth of fetuses, in Long Evans rats at 100 mg/kg/day administered by gavage from day 6 through day 15 of pregnancy. 3-12 h yDecreases heart rate and no increase in myocardial ySedation in up to 50% ... possibly CNS effects yHeart failure; reactive airway disease; second and third degree heart block; no dose which will reliably lower BP within a couple of hours in the majority of patients. Comparitive study of nimodipine versus Nifedipine in the treatment of hyperstion in pregnancy Dr.Veena B.T.1, Dr.Suvarna R2 1 ... acute and chronic hypertensions has long side effects like rapid drop in the pressure following medication, complications like Myocardial infarction and Congestive cardiac failure3. The terminal elimination half-life is approximately 8 to 9 hours but earlier elimination rates are much more rapid, equivalent to a half-life of 1 to 2 hours; a consequence is the need for frequent (every 4 hours) dosing. In the second study an increased incidence of stunted fetuses was seen at 1 mg/kg/day but not at higher doses. Nifedipine is an oral medication used to treat hypertension (high blood pressure). Each liquid filled capsule contains 30 mg of Nimodipine in a vehicle of glycerin, peppermint oil and polyethylene glycol. If the person taking nimodipine cannot swallow the capsule, the medicine from inside the capsule can be given through a Your blood pressure and heart rate will need to be checked often. Nimodipine inhibits calcium ion transfer into these cells and thus inhibits contractions of vascular smooth muscle. DO NOT ADMINISTER Nimodipine INTRAVENOUSLY OR BY OTHER PARENTERAL ROUTES. This is not a complete list of side effects and others may occur. Dosage should be reduced to one 30 mg capsule every 4 hours with close monitoring of blood pressure and heart rate; if necessary, discontinuation of the treatment should be considered.Strong inhibitors of CYP3A4 should not be administered concomitantly with Nimodipine (see Manufactured for: The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. blockers. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. You should not use nimodipine if you are allergic to it.It is not known whether this medicine will harm an unborn baby. Drug information contained herein may be time sensitive. Available for Android and iOS devices. Verapamil and related drugs are also vasodilators, with an additional depressant effect on atrioventricular conduction, heart rate and contractility. 6 Aluminum Lake, gelatin, glycerin, iron oxide black, lecithin, medium-chain triglycerides, shellac, sorbitol and titanium dioxide.Nimodipine is a calcium channel blocker. Store at room temperature away from moisture, heat, and light.