Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people. Repeat, if necessary, for the opposite ear (see DOSAGE AND ADMINISTRATION). Discontinue use immediately and contact your physician at the first sign of a rash or allergic reaction.Prior to administration of ofloxacin otic solution, the solution should be warmed by holding the bottle in the hand for one or two minutes to avoid dizziness which may result from the instillation of a cold solution. Your list will be saved and can be edited at any time.The above information is provided for general Use only as directed. Serious acute hypersensitivity reactions may require immediate emergency treatment.
Follow your doctor's orders or the directions on the label.
Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.
Individual plans may vary
The patient should lie with the affected ear upward, before instilling the drops.
The chemical name of ofloxacin is: (±)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzoxazine-6-carboxylic acid.
Five drops (0.25 mL, 0.75 mg ofloxacin) instilled into the affected ear twice daily for ten days. Also, a fluid discharge may appear in the ear canal.The person giving ofloxacin otic solution should wash his/her hands with soap and water.Gently clean any discharge that can be removed easily from the outer ear.DO NOT INSERT ANY OBJECT OR SWAB INTO THE EAR CANAL.Hold the bottle of ofloxacin otic solution in the hand for one or two minutes to warm the solution.The person receiving ofloxacin otic solution should lie on his/her side with the infected ear up. Ofloxacin belongs to the family of medicines called antibiotics. The following treatment-related adverse events were each reported in a single subject: application site reaction, otitis externa, urticaria, abdominal pain, dysaesthesia, hyperkinesia, halitosis, inflammation, pain, insomnia, coughing, pharyngitis, rhinitis, sinusitis, and tachycardia.Cases of uncommon transient neuropsychiatric disturbances have been included in spontaneous post-marketing reports. Ofloxacin otic solution is used to treat infections of the ear canal. and formulary information changes. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research.© 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). Instill 10 gtt twice daily for 14 days in affected ear(s)>12 years: Instill 10 gtt twice daily for 14 days in affected ear(s)May result in overgrowth of nonsusceptible organisms, including fungiCareful monitoring, including slit-lamp biomicroscopy and fluorescein staining when appropriate, may be necessary in some patients receiving topical ophthalmic ofloxacin therapyLactation: Not known if distributed in milk; not recommendedA: Generally acceptable. Therefore, it may not be known whether they work exactly the same way they do in younger adults or if they cause different side effects or problems in older people.
Many medicines have not been studied specifically in older people. ... Ofloxacin / administration & dosage* Because of the potential for serious adverse reactions from ofloxacin in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.Safety and efficacy have been demonstrated in pediatric patients of the following ages for the listed indications:Safety and efficacy in pediatric patients below these ages have not been established.Although no data are available on patients less than age 6 months, there are no known safety concerns or differences in the disease process in this population that will preclude use of this product.No changes in hearing function occurred in 30 pediatric subjects treated with ofloxacin otic and tested for audiometric parameters.Although quinolones, including ofloxacin, have been shown to cause arthropathy in immature animals after systemic administration, young growing guinea pigs dosed in the middle ear with 0.3% ofloxacin otic solution for one month showed no systemic effects, quinolone-induced lesions, erosions of the cartilage in weight-bearing joints, or other signs of arthropathy.In the phase III clinical trials performed in support of once-daily dosing, 799 subjects with otitis externa and intact tympanic membranes were treated with ofloxacin otic solution. The solution should be warmed by holding the bottle in the hand for one or two minutes to avoid dizziness that may result from the instillation of a cold solution. If the pain is severe, the medication should be stopped and you should contact your doctor.