Controlled studies in pregnant women show no evidence of fetal risk.Uterine stimulant, vasopressive, & antidiuretic effects; activates G-protein-coupled receptors that trigger increases in intracellular calcium levels in uterine myofibrils, which results in uterine contractions; increases local prostaglandin production, which further stimulates uterine contractionMetabolism: Rapidly metabolized in the liver and plasmaHalf-Life: 1-6 min; decreased in late pregnancy and during lactationAdditive: chloramphenicol sodium succinate, metaraminol, netilmicin, sodium bicarbonate, thiopental, verapamilY-site: heparin, hydrocortisone sodium succinate, insulin, meperidine, morphine sulfate, KCl, vitamin B/C, warfarinDilute to 10 mU/mL by adding 10 U (1 mL) to 1000 mL of D5W, LR, or NSAdminister by IV infusion using infusion control device, orDo not use solution if discolored or contains precipitateAdding plans allows you to compare formulary status to other drugs in the same class.To view formulary information first create a list of plans. Side effects, drug interactions, and patient safety information should be reviewed prior to taking this medication. Preeclampsia symptoms include rapid weight gain, abdominal pain, headaches, blood in the urine, dizziness, and excessive vomiting and nausea. Oxytocin (Pitocin) is an injectable drug used for inducing labor, controlling bleeding after childbirth, and for the treatment of incomplete or inevitable abortion. Third trimester symptoms are additional weight gain, heartburn, hemorrhoids, swelling of the ankles, fingers, and face, breast tenderness, and trouble sleeping. Isordil: pharmacologic class. Continuous IV infusion gives a gradual response reaching steady state within 20-40 mins. Davis Company PDF Page #2 2 PotentialNursingDiagnoses MedicineNet does not provide medical advice, diagnosis or treatment. Diseases & Conditions According to Nature of Action 4. Medically reviewed by John P. Cunha, DO, FACOEP; Board Certified Emergency MedicineWhat is oxytocin-injectable, and how does it work (mechanism of action)?What brand names are available for oxytocin-injectable?Is oxytocin-injectable available as a generic drug?Is oxytocin-injectable safe to take if I'm pregnant or breastfeeding? Second trimester symptoms include backache, weight gain, itching, and possible stretch marks. provider for the most current information.The recipient will receive more details and instructions to access this offer.By clicking send, you acknowledge that you have permission to email the recipient with this information.The recipient will receive more details and instructions to access this offer.By clicking send, you acknowledge that you have permission to email the recipient with this information. Add 10-40 units; not to exceed 40 units; to 1000 mL of nonhydrating IV solution and infuse at necessary rate to control uterine atony0.5-1 mUnit/min IV, titrate 1-2 mUnit/min q15-60min until contraction pattern reached that is similiar to normal labor (usually 6 mUnits/min); may decrease dose after desired frequency of contraction reached and labor has progressed to 5-6 cm dilationOrphan designation for treatment of Prader-Willi syndromeSinus bradycardia, tachycardia, premature ventricular complexes & other arrhythmiasPermanent CNS or brain damage, and death secondary to asphyxiaUteroplacental hypoperfusion & variable deceleration of fetal heart rateSevere decreases in maternal systolic & diastolic blood pressure, increases in heart rate, systemic venous return & cardiac output, & arrhythmiaElective induction of labor is defined as the initiation of labor in a pregnant individual who has no medical indications for induction.Because the available data are inadequate to evaluate the benefits-to-risks onsiderations, oxytocin is not indicated for elective induction of labor.Unfavorable fetal positions or presentations, eg, transverse lies,which are undeliverable without conversion prior to deliveryWhere adequate uterine activity fails to achieve satisfactory progressContraindicated vaginal delivery, eg, invasive cervical carcinoma, active herpes genitalis, total placenta previa, vasa previa, & cord presentation or prolapse of cordFetal distress, polyhydramnios, partial placenta previa, prematurity, borderline cephalopelvic disproportion, previous major surgery of cervix or uterus (incl C-section), overdistension of uterus, grand multiparity, invasive cervical carcinoma, history of uterine sepsis or traumatic deliveryHyperstimulation of the uterus, with strong (hypertonic) &/or prolonged (tetanic) contractions, or a resting uterine tone of 15-20 mm H2O between contractions may occur, possibly resulting in uterine rupture, cervical & vaginal lacerations, postpartum hemorrhage, abruptio placentae, impaired uterine blood flow, amniotic fluid embolism, & fetal trauma including intracranial hemorrhageIf uterine hyperactivity occurs, discontinue immediatelyIntravenous preparations should be be administered by trained personnelRisk of severe water intoxication on prolonged administration due to its antidiuretic effectsUterine hypertonicity, spasm, rupture of the uterus, and tetanic contractions may occur from high dosesIM not recommended for labor induction/augmentationLactation: May be distributed milk; commencement of nursing should be delayed for at least 1 day when discontinued; use cautionA: Generally acceptable.