Diarrhea was also reported higher in the treatment group than the placebo arm. It also has a broader benefit in that it also reduces lower respiratory tract infections, improves quality of life and it costs significantly less. improved quality of life when treated with oral azithromycin for 48 weeks. The safety, immunogenicity, and acceptability of inactivated influenza vaccine delivered by microneedle patch (TIV-MNP 2015): a randomised, partly blinded, placebo-controlled, phase 1 trialFoley catheterisation versus oral misoprostol for induction of labour in hypertensive women in India (INFORM): a multicentre, open-label, randomised controlled trialAccess any 5 articles from the Lancet Family of journals The proportion of patients experiencing at least one asthma exacerbation might be a useful add-on therapy in persistent asthma. That’s why new research from Australia suggesting that the antibiotic azithromycin (Zithromax) for asthma is so exciting.The authors called their trial AMAZES (Asthma and Macrolides: AZithromycin Efficacy and Safety study).The results were very good if not amazing. A randomized trial looked at adding the antibiotic azithromycin (this antibiotic is commonly known as Z-pack) for patients with severe asthma that was uncontrolled by inhaled corticosteroids and long acting bronchodilators. National Health and Medical Research Council of Australia, John Hunter Hospital Charitable Hard-to-treat asthma can be a life-threatening lung disease. Quibron-tActive ingredient: Theophylline $0.43 for pill Quibron-T (Theophylline) is a bronchodilator used to treat the symptoms of asthma, chronic bronchitis, and emphysema. Buy Erectile Dysfunction - Permitil (Brand name: brand viagra) online without a doctor's prescription Brand Viagra is often the first treatment tried for erectile dysfunction in men and pulmonary arterial hypertension. To read this article in full you will need to make a paymentUncontrolled asthma: a review of the prevalence, disease burden and options for treatment.Clinical burden and predictors of asthma exacerbations in patients on guideline-based steps 4–6 asthma therapy in the TENOR cohort.Effect of asthma exacerbations on health care costs among asthmatic patients with moderate and severe persistent asthma.Inflammatory subtypes in asthma: assessment and identification using induced sputum.Azithromycin induces anti-viral responses in bronchial epithelial cells.Immunomodulatory effects of macrolide antibiotics—part 2: advantages and disadvantages of long-term, low-dose macrolide therapy.Clarithromycin targets neutrophilic airway inflammation in refractory asthma.Azithromycin for prevention of exacerbations in severe asthma (AZISAST): a multicentre randomised double-blind placebo-controlled trial.Macrolide antibiotics for treatment of asthma in adults: a meta-analysis of 18 randomized controlled clinical studies.Macrolides for the long-term management of asthma—a meta-analysis of randomized clinical trials.Development and validation of a questionnaire to measure asthma control.Full blood count parameters for the detection of asthma inflammatory phenotypes.An official American Thoracic Society/European Respiratory Society statement: asthma control and exacerbations: standardizing endpoints for clinical asthma trials and clinical practice.Validation of a standardized version of the Asthma Quality of Life Questionnaire.Determining asthma treatment by monitoring sputum cell counts: effect on exacerbations.Analysis of exacerbation rates in asthma and chronic obstructive pulmonary disease: example from the TRISTAN study.Azithromycin for bronchial asthma in adults: an effectiveness trial.Azithromycin: mechanisms of action and their relevance for clinical applications.A trial of clarithromycin for the treatment of suboptimally controlled asthma.Cyclosporin A and FK506 reduce interleukin-5 mRNA abundance by inhibiting gene transcription.Rapamycin inhibition of eosinophil differentiation attenuates allergic airway inflammation in mice.Macrolide antibiotics and the risk of cardiac arrhythmias.The effect of long-term macrolide treatment on respiratory microbiota composition in non-cystic fibrosis bronchiectasis: an analysis from the randomised, double-blind, placebo-controlled BLESS trial.Immunomodulatory effects of a low-dose clarithromycin-based macrolide solution pressurised metered dose inhaler.Anti-inflammatory effects of a novel non-antibiotic macrolide, EM900, on mucus secretion of airway epithelium.Combination formoterol and budesonide as maintenance and reliever therapy versus combination inhaler maintenance for chronic asthma in adults and children. Azithromycin could be considered in patients with severe uncontrolled asthma who are already taking high doses of inhaled corticosteroids and long acting beta agonists before the introduction of monoclonal antibodies. 1.61$. These results demonstrate that azithromycin may be of benefit for add on therapy for patients with severe asthma.A major downside of using azithromycin that frequently would be the development of antibiotic resistance.