Signs of a severe allergic reaction can include hives, swelling of the face and throat, difficulty breathing, a fast heartbeat, dizziness, and weakness. Discard if the reconstituted vaccine has been frozen.SHINGRIX is a recombinant vaccine for intramuscular injection only.The second dose should be administered anytime between 2 and 6 months after the first dose to complete the 2-dose series as directed.Following the first dose of SHINGRIX, the second dose should be given 2-6 months laterThe efficacy of alternative dosing regimens has not been evaluatedData regarding the safety of alternative regimens are limitedIndividuals might remain at risk for herpes zoster during a longer than recommended interval between doses 1 and 2*In a phase 3 clinical study designed to help establish the dosing interval for SHINGRIX, all primary endpoints were met for dosing at a 0- and 6-month interval when compared to dosing at a 0-and 2-month interval. If more than 6 months have elapsed since the first dose, administer the second dose as soon as possible. About 1 out of 10 adults who received Shingrix reported grade 3 injection-site symptoms such as pain, redness, and swelling. Please modify your settings or use a different browser to continueYou now have access to the latest updates, events and resources.You now have sucesfully register for the event and you can also access the latest updates, events and resources.In case you would like to receive SMS-reminders for the event you have registered, please scroll down to provide your mobile number.In case you would like to receive sms-reminders for the event you have registered, please update your In case you would like to receive sms-reminders for the event you have registered, please update your You are leaving GSK Pro to visit a separate website not associated with GSK Pro, a portal for US Healthcare Professionals.There are website links to third-party sites on GSK Pro. After you receive the first dose, you can get the second dose two to six months later. Two doses of Shingrix is more than 90% effective at preventing shingles and PHN. After reconstitution, administer SHINGRIX immediately or store refrigerated between 2°C and 8°C (36°F to 46°F) and use within 6 hours. However, you may suggest patients take over-the-counter ibuprofen or acetaminophen to ease discomfort from side effects.If a patient has a reaction to the first dose of Shingrix it does not necessarily mean they will have a reaction to the second dose. Discard reconstituted vaccine if not used within 6 hours.Use a separate sterile needle and sterile syringe for each individual. Shingrix is not indicated for prevention of primary varicella infection (chickenpox). Remember that the pain from shingles can last a lifetime, and these side effects should only last 2 to 3 days.The impact of prophylactic analgesics in conjunction with Shingrix has not been studied. Shingrix is a vaccine indicated for prevention of herpes zoster (shingles) in adults aged 50 years and older. Get the second dose of Shingrix even if you have a reaction after the first dose. In a clinical trial of more than 30,000 participants, vaccine efficacy was 96.6% in adults age 50 to 59 years, 97.4% in adults age 60 to 69 years, and 91.3% in adults age 70 years and older. 1 CDC has issued guidance on the SHINGRIX dosing schedule 2 , 3 , * Years ago, I received one dose, although I forget the name of it. Do not restart the vaccine series, and do not substitute Zostavax® (zoster vaccine live) for the second dose of Shingrix. According to the CDC if, by accident, the second dose is administered less than 4 weeks after the first, … You should plan to avoid strenuous activities, such as yardwork or swimming, for a few days after vaccination. However, a co-primary endpoint (noninferiority) of the immune response was missed for dosing at a 0- and 12-month interval. The preferred site for intramuscular injection is the deltoid region of the upper arm.Two doses (0.5 mL each) administered intramuscularly according to the following schedule: A first dose at Month 0 followed by a second dose administered anytime between 2 and 6 months later.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records.