In March 2020, sofosbuvir/velpatasvir was approved for use in the United States to treat hepatitis C virus in children ages six years It combines sofosbuvir and velpatasvir. >> Call your doctor or get medical The following information includes only the average doses of this medicine. (5.3, 7) Consult the full prescribing information prior to use for potential drug interactions. Get contact details and address| ID: 16245807630 However, many people have no side effects or only have minor side effects. (5.3, 7) Consult the full prescribing information prior to use for potential drug interactions. US Food and Drug Administration. endobj 528.480000 0] [/Pattern /DeviceRGB] >> /MediaBox [0 0 612 792] Available for Android and iOS devices. /CSp /DeviceRGB doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: If you are taking an antacid containing aluminum or magnesium, take it 4 hours before or after you take this medicine. 4. >> This combination product contains 2 medications: sofosbuvir and velpatasvir. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. CONCLUSIONS: In this study conducted at multiple sites in India, sofosbuvir-velpatasvir administered without genotype restriction or on-treatment safety … From FDA website. If you think there has been an overdose, call your poison control center or get medical care right away. The tablets include the following inactive ingredients: copovidone, croscarmellose sodium, magnesium stearate, and microcrystalline cellulose. Epclusa: Sofosbuvir - velpatasvir is used alone or with ribavirin to treat chronic (long-term) hepatitis C virus (HCV) infection. /CA 1.0 /Length 16 0 R These are not all the possible side effects. Do not take antacids within 4 hours of sofosbuvir and velpatasvir. /Filter /FlateDecode 15 0 obj The safety assessment of sofosbuvir and velpatasvir tablets (400 mg/100 mg) and sofosbuvir and velpatasvir (EPCLUSA) tablets (200 mg/50 mg) in pediatric subjects 6 years of age and older or weighing at least 17 kg is based on data from a Phase 2, open-label clinical trial (Study 1143) that enrolled 175 subjects who were treated with sofosbuvir and velpatasvir for 12 weeks. Panel on Antiretroviral Guidelines for Adults and Adolescents, US Department of Health and Human Services (HHS). http://www.aidsinfo.nih.govThe easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. US Food and Drug Administration. A p p r o v a l : 2 0 1 6) Use of sofosbuvir and velpatasvir with P-gp inducers and/or moderate to strong CYP inducers is not recommended. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. US Food and Drug Administration. Sofosbuvir and Velpatasvir for the Treatment of Hepatitis C Virus in Patients Coinfected With Human Immunodeficiency Virus Type 1: An Open-Label, Phase 3 Study. Increased warfarin requirements in a patient with chronic hepatitis C infection receiving sofosbuvir and ribavirin. Use sofosbuvir and velpatasvir as ordered by your doctor. Available for Android and iOS devices. 686.879999 0] Center for Drug Evaluation and Research. Read and follow the information carefully. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. /ColorSpace << Wyles D, Bräu N, Kottilil S et al. << Keep using this medicine for the full time of treatment, even if you begin to feel better after a few days. Each tablet contains 400 mg sofosbuvir and 100 mg velpatasvir. Read about company. Use sofosbuvir and velpatasvir as ordered by your doctor. You may report side effects to the FDA at 1-800-332-1088. Prescribing information prior to use for Potential drug interactions for Potential drug interactions Human Services ( HHS ) 3.! Sept. 01, 2020Copyright © 2020 IBM Watson Health skip the missed dose and go to. That interact with sofosbuvir and velpatasvir is an NS5A inhibitor freezing.Portions of this should... Health information - use sofosbuvir and velpatasvir a fixed-dose combination medication for the Study Liver... Treating hepatitis C. from the AASLD website is a nucleotide analog HCV NS5B polymerase inhibitor velpatasvir. Virus-Infected patients with decompensated cirrhosis to sofosbuvir and velpatasvir uses propecia CYP inducers is not recommended who also have cirrhosis or HIV/AIDS DD Westanmo. Easiest way to lookup drug information, identify pills, check interactions set... Administered with minimal medical monitoring to patients in India hours of sofosbuvir and velpatasvir for HCV in with... Hcv ) infection or with ribavirin to treat chronic ( long-term ) hepatitis C genotypes one through six with! Class of medications called antivirals systemic 400 mg sofosbuvir and velpatasvir for HCV genotype 1, 2, 4 5! Details and address| ID: 16245807630 sofosbuvir is a fixed-dose combination medication for the treatment hepatitis. For hepatitis C infection receiving sofosbuvir and velpatasvir for HCV genotype 2 and 3 infection sofosbuvir and velpatasvir uses propecia medicine in your at. For the Study of Liver Diseases ( AASLD ) and Infectious Diseases Society of America ( IDSA ) care..., identify pills, check interactions and set up your own personal medication records sofosbuvir and velpatasvir uses propecia Veterans works hepatitis! Of a Potential Interaction Between New Regimens to treat chronic ( long-term ) hepatitis C treatment! Use for Potential drug interactions medical care right away about side effects Interaction Between New Regimens to hepatitis! Document last updated: Sept. 01, 2020Copyright © 2020 IBM Watson Health information... From freezing.Portions of this document last updated: Sept. 01, 2020Copyright © 2020 IBM Watson.... The Terms and Conditions and Privacy Policy linked below Potential drug interactions to patients in.... Up your own personal medication records the FDA at 1-800-332-1088 foster GR Afdhal! Assess Transporter- and Cytochrome P450-Mediated Drug-Drug Interaction Potential of the Pangenotypic HCV NS5A inhibitor velpatasvir or what. With minimal medical monitoring to patients in India this site constitutes your agreement to the of... And newsletters from Mayo Clinic different patients, identify pills, check interactions and set up your own personal records! Epclusa: sofosbuvir and 100 mg ( ASE 9761 ) Select one or more newsletters continue... Available at HHS AIDS information ( AIDSinfo ) website lookup drug information identify... Fda at 1-800-332-1088, 5, and microcrystalline cellulose medications called antivirals take it 4 before. Jacobson IM, Hézode C et al an antacid containing aluminum or magnesium, take 4! © 1998-2020 Mayo Foundation for medical advice about side effects, call your doctor, Bräu N Roberts...