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Tenofovir alafenamide, a hepatitis B virus (HBV) nucleoside analog reverse transcriptase inhibitor, is converted in vivo to tenofovir, an acyclic nucleoside phosphonate (nucleotide) analog of adenosine 5′-monophosphate. endstream
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h��V�k�0�W��=ɲ$�P Tenofovir (TFV) is a nucleotide analogue with limited oral bioavailability that inhibits HIV -1 reverse transcription. The retention time of the major peak from the Sample Tenofovir Disoproxil Fumarate. Tenofovir is one of the newer, more tolerable, nucleotide reverse transcriptase inhibitors on the market; is a mainstay of many antiretroviral therapy combinations; and is now available in 2 different formulations, tenofovir disoproxil fumarate (TDF) and, the more recent, tenofovir alafenamide (TAF).
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Use tenofovir alafenamide as ordered by your doctor. It is important that you do not miss or skip a dose of tenofovir alafenamide during treatment. Tenofovir alafenamide fumarate is a fumarate salt prepared from tenofovir alafenamide by reaction of one molecule of fumaric acid for every two molecules of tenofovir alafenamide.A prodrug for tenofovir, it is used in combination therapy for the treatment of HIV-1 infection.It has a role as an antiviral drug, a HIV-1 reverse transcriptase inhibitor and a prodrug. %%EOF
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