A conservative titration scheme is recommended for patients at increased risk for hypoglycemia Patients being transferred to AMARYL from longer half-life sulfonylureas (e.g., chlorpropamide) may have overlapping drug effect for 1 to 2 weeks and should be appropriately monitored for hypoglycemia.When colesevelam is coadministered with glimepiride, maximum plasma concentration and total exposure to glimepiride is reduced. Select one or more newsletters to continue. Do not double doses.Store the medicine in a closed container at room temperature, away from heat, moisture, and direct light. Patients at increased risk for hypoglycemia (e.g., the elderly or patients with renal impairment) should be started on 1 mg once daily After reaching a daily dose of 2 mg, further dose increases can be made in increments of 1 mg or 2 mg based upon the patient's glycemic response. The following information includes only the average doses of this medicine. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. Do not take more of it, do not take it more often, and do not take it for a longer time than your doctor ordered. It may help to improve your mood, appetite, and energy level as well as decrease anxiety and insomnia related to depression. Learn about side effects, drug interactions, dosages, warnings, and more. This medicine should come with a Medication Guide. Trazodone is approved by the FDA as a prescription drug used for the medical treatment of depression. To lessen stomach upset and to reduce dizziness and lightheadedness, take the regular tablet with or shortly after a meal or light snack. Available for Android and iOS devices. Read and follow these instructions carefully. Observe patients carefully for 1-2 weeks when being converted from long half-life sulfonylureas to glimepiride, because of potential for overlapping of hypoglycemic effects Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine.If you miss a dose of this medicine, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not break the tablet unless your doctor tells you to. If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. Information is for End User's use only and may not be sold, redistributed or otherwise used for commercial purposes.Mayo Clinic does not endorse companies or products. The dose of this medicine will be different for different patients. Ask your doctor or pharmacist if you have any questions. AMARYL should be administered with breakfast or the first main meal of the day.The recommended starting dose of AMARYL is 1 mg or 2 mg once daily. © 1998-2020 Mayo Foundation for Medical Education and Research (MFMER). The following information includes only the average doses of this medicine. Follow your doctor's orders or the directions on the label. Usual Geriatric Dose for Diabetes Type 2 Initial dose: 1 mg orally once a day; titrate slowly and monitor closely Usual Pediatric Dose for Diabetes Type 2 Not recommended because of adverse effects on body weight and hypoglycemia. Conversion from other oral hypoglycemic agents. This is an off-label use of this antidepressant. We comply with the HONcode standard for trustworthy health information - The recommended starting dose of AMARYL is 1 mg or 2 mg once daily. Uptitration should not occur more frequently than every 1 to 2 weeks. Trazodone works by helping to restore the balance of a certain natural chemical (serotonin) in … Trazodone is used to treat major depressive disorder. All rights reserved. If your dose is different, do not change it unless your doctor tells you to do so.The amount of medicine that you take depends on the strength of the medicine. Keep from freezing.Do not keep outdated medicine or medicine no longer needed.Ask your healthcare professional how you should dispose of any medicine you do not use.Portions of this document last updated: Sept. 01, 2020Copyright © 2020 IBM Watson Health. Initial: 1-2 mg PO qAM after breakfast or with first meal; may increase dose by 1-2 mg every 1-2 weeks; not to exceed 8 mg/day. Trazodone is often prescribed for sleep. When the time comes to withdraw trazodone, the dosage should be tapered off slowly under a doctor's advice.