Trihexyphenidyl is also used to treat and prevent Parkinson-like symptoms that are caused by using certain anti-psychotic medications. Cortex 20 (1984): 307-1118. Can J Psychiatry 31 (1986): 339-417. McEvoy JP, Freter S "The dose-response relationship for memory impairment by anticholinergic drugs." However, it has been clinically relevant in trials pertaining to Parkinson's disease since 1949. 1. Prog Neuropsychopharmacol Biol Psychiatry 6 (1982): 75-8227. Wilcox JA "Psychoactive properties of benztropine and trihexyphenidyl." Trihexyphenidyl is used to treat symptoms of Parkinson's disease (stiffness, tremors, spasms, poor muscle control). In a group of 22 psychiatric patients receiving long‐term anti‐psychotic medication concurrently with trihexyphenidyl the effects of trihexyphenidyl withdrawal were studied double‐blind and placebo controlled. Blumensohn R, Razoni G, Shalev A, Munitz H "Bradycardia due to trihexyphenidyl hydrochloride." Am J Psychiatry 134 (1977): 1038-4021. Drug Intell Clin Pharm 20 (1986): 786-726. and you may need to create a new Wiley Online Library account.Enter your email address below and we will send you your usernameIf the address matches an existing account you will receive an email with instructions to retrieve your username Available for Android and iOS devices. Warne RW, Gubbay SS "Choreiform movements induced by anticholinergic therapy." Along with its needed effects, trihexyphenidyl may cause some unwanted effects. If you do not receive an email within 10 minutes, your email address may not be registered, McEvoy JP "A double-blind crossover comparison of antiparkinson drug therapy: amantadine versus anticholinergics in 90 normal volunteers, with an emphasis on differential effects on memory function." Trihexyphenidyl may also be used for purposes not listed in this medication guide. Can Psychiatr Assoc J 23 (1978): 163-5. Med J Aust 1 (1979): 46511. It’s also used to … Am J Psychiatry 130 (1973): 141-513. Mov Disord 8 (1993): 512-410. 2. Please check your email for instructions on resetting your password. Stephens DA "Psychotoxic effects of benzhexol hydrochloride (Artane)." Laski E, Taleporos E "Anticholinergic psychosis in a bilingual: a case study." Can J Psychiatry 30 (1985): 440-214. Symptoms include delusions, hallucinations, aggression or violent behavior, and suicidal tendencies. Am J Psychiatry 144 (1987): 573-712. el-Yousef MK, Janowsky D, Davis JM, Sekerke HJ "Reversal of antiparkinsonian drug toxicity by physostigmine: a controlled study." However, occasionally the onset may be delayed by months. Kiloh LG, Smith JS, Williams SE "Antiparkinson drugs as causal agents in tardive dykinesia." 1. … Tablets: Containing 2 mg and 5 mg ARTANE (trihexyphenidyl HCl), each strength also containing as inactive ingredients: Corn Starch, Dibasic Calcium Phosphate, Magnesium Stearate and Pregelatinized Starch. Can Psychiatr Assoc J 23 (1978): 163-53. Kulik AV, Wilbur R "Delirium and stereotypy from anticholinergic antiparkinson drugs." Yassa R "Antiparkinsonian medication withdrawal in the treatment of tardive dyskinesia: a report of three cases." "Product Information. J Psychoactive Drugs 15 (1983): 319-2122. J Clin Psychiatry 47 (1986): 523-45. An investigation of mechanism." J Clin Psychiatry 42 (1981): 313-7Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Some side effects may not be reported. Neuropsychobiology 6 (1980): 109-2019. generic drugs) are not considered. West RR, Newgreen DB "Choreiform movements induced by anticholinergic therapy." Kalman T, Warner GM "Protracted vomiting following abrupt cessation of psychotropics: a case report." Withdrawal. Baker LA, Cheng LY, Amara IB "The withdrawal of benztropine mesylate in chronic schizophrenic patients." Hussey HH "Physostigmine: value in treatment of central toxic effects of anti-cholinergic drugs." Acta Neurol Scand 50 (1974): 801-119. Moreau A, Jones BD, Banno V "Chronic central anticholinergic toxicity in manic depressive illness mimicking dementia." Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Warnes H "Toxic psychosis due to antiparkinsonian drugs." Other drugs that have the same active ingredients (e.g. Artane, or its generic form Trihexyphenidyl HCL, was approved by the FDA on June 25th, 2003 for the clinical use of all types of parkinsonism. Br J Psychiatry 143 (1983): 584-904. Br J Psychiatry 113 (1967): 213-824. Br Med J 1 (1972): 60525. Compr Psychiatry 30 (1989): 135-816. Med J Aust 2 (1979): 87-88. Trihexyphenidyl withdrawal encephalopathy. J Neurol Neurosurg Psychiatry 52 (1989): 111523.