Cerner Multum, Inc. "Australian Product Information." Increased serum creatinine was reported within the first 4 weeks of therapy and remained stable through 144 weeks. In general, laboratory abnormalities were similar in therapy-experienced patients.The rates of AST and ALT abnormalities were higher in patients coinfected with hepatitis B and/or C virus (HBV and/or HCV). Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. TRIUMEQ can cause serious side effects, including: Serious allergic reactions (hypersensitivity reaction) that can cause death have happened with TRIUMEQ and other abacavir-containing products. TRIUMEQ can cause serious side effects, including:. Rarely, life-threatening reactions have occurred within hours after restarting abacavir in patients who stopped it for reasons other than symptoms of hypersensitivity (or who stopped it with only 1 key symptom of hypersensitivity).-Postmarketing reports: Sensitization reactions (including anaphylaxis)-Common (1% to 10%): Hypersensitivity reactions (including fever, rash [maculopapular, urticarial], generalized malaise, fatigue, achiness, nausea, vomiting, diarrhea, abdominal pain, pharyngitis, dyspnea, cough, lethargy, headache, myalgia, myolysis, edema, abnormal chest x-ray findings [mainly localized infiltrates], arthralgia, paresthesia, anaphylaxis, hepatitis, liver failure, renal failure, hypotension, sore throat, adult respiratory distress syndrome, respiratory failure, death, lymphadenopathy, mucous membrane lesions [conjunctivitis, mouth ulcerations], -Frequency not reported: Hypersensitivity reactions (characterized by rash, constitutional findings, and sometimes organ dysfunction, including liver injury)Grade 2 and grade 3 to 4 elevations in AST were reported in up to 3% and up to 1% of therapy-naive patients, respectively. Read all information given to you. If you have questions about side effects, call your doctor. O 03. Abacavir hypersensitivity was reported in about 8% of patients in 9 clinical trials with abacavir-containing products where patients were not screened for the HLA-B*5701 allele; incidence of suspected abacavir hypersensitivity reactions was 1% in clinical trials where HLA-B*5701 carriers were excluded.Abacavir hypersensitivity reactions have been characterized by at least 2 of the following key signs/symptoms: (1) fever; (2) rash; (3) gastrointestinal symptoms (including nausea, vomiting, diarrhea, Symptoms of abacavir hypersensitivity reaction worsened with continued therapy and generally resolved when abacavir was discontinued. Check with your doctor and pharmacist to make sure that it is safe for you to take Triumeq (abacavir, dolutegravir, and lamivudine) with all of your other drugs (prescription or OTC, natural products, vitamins ). Meta-analysis of randomized, controlled clinical trials showed no excess risk of MI in abacavir-treated patients as compared with control subjects. taken, how much, and when it happened. You may also report side effects at https://www.fda.gov/medwatch. If any of these effects persist or worsen, notify your doctor or pharmacist promptly.. Call your doctor or get medical Stomach upset, headache, nausea, vomiting, or diarrhea may occur. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Restarting abacavir after a hypersensitivity reaction has resulted in more severe symptoms within hours and included life-threatening hypotension and death. help if any of these side effects or any other side effects bother you or do not go away: DTG is the third integrase inhibitor to be approved (in January 2014 in Europe) and is available as an individual agent for once-daily dosing or in a fixed drug combination with abacavir and lamivudine, branded under the trade name Triumeq . DOLUTEGRAVIR. Call your doctor for medical ALT abnormalities (grade 2 to 4) were reported in 15% and 2% of HIV/HCV-coinfected patients and HIV-monoinfected patients, respectively.Transaminase elevations were consistent with immune reconstitution syndrome or hepatitis B reactivation in some patients with underlying hepatitis B and/or C, especially when antihepatitis therapy was stopped.Hepatic decompensation (some fatal) has been reported in patients coinfected with HIV-1 and HCV receiving combination antiretroviral therapy for HIV-1 and interferon alfa with or without Severe acute exacerbations of hepatitis have been reported in patients with hepatitis B after discontinuation of lamivudine.-Frequency not reported: Liver function test abnormalities, severe hepatomegaly with steatosis-Postmarketing reports: Acute liver failure, liver transplant-Frequency not reported: Liver function test abnormalities, elevated liver chemistries (AST, ALT, alkaline phosphatase, bilirubin)-Frequency not reported: Transaminase elevations (consistent with immune reconstitution syndrome or hepatitis B reactivation), hepatic toxicity (including elevated serum liver biochemistries, hepatitis, acute liver failure)-Frequency not reported: Elevated bilirubin, hepatic decompensation, severe acute exacerbations of hepatitisGrade 2 and grade 3 to 4 elevations in lipase were reported in up to 11% and up to 5% of therapy-naive patients, respectively. : //www.fda.gov/medwatch of medications called human triumeq side effects on kidneys cefaclor virus ( HIV ) integrase transfer... 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