It is important to tell your doctor about all other medications you use, including vitamins and herbs. if you have suddenly stopped using alcohol, seizure medication, or a sedative (such as Xanax, Valium, Fiorinal, Klonopin, and others). Select one or more newsletters to continue. Antidepressants and DXM The list of major medication interactions between antidepressants and dextromethorphan (DXM) , a common ingredient in cough medicine, is extensive. https://www.webmd.com/drugs/2/drug-13509/wellbutrin-oral/details You should not take Wellbutrin XL if you are allergic to it, or if you have: a seizure disorder; an eating disorder such as anorexia or bulimia; or. Report any new or worsening symptoms to your doctor.You should not take Wellbutrin XL if you are allergic to it, or if you have:if you have suddenly stopped using alcohol, seizure medication, or a sedative (such as Do not use an MAO inhibitor within 14 days before or 14 days after you take Wellbutrin XL. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Stopping suddenly can cause unpleasant withdrawal symptoms. The other night I wasn't feeling well. If you’ve taken a medication with dextromethorphan in it, your drug screen may be positive for opiates and PCP (phencyclidine). Do not stop using any medications without first talking to your doctor.Using buPROPion with alcohol may increase the risk of uncommon side effects such as seizures, hallucinations, delusions, paranoia, mood and behavioral changes, depression, suicidal thoughts, anxiety, and panic attacks. This includes prescription and over-the-counter medicines, Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.Copyright 1996-2018 Cerner Multum, Inc. Some people may also experience impairment in thinking and judgment. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Why Are Dementia Patients Getting Risky Psychiatric Drugs? On the other hand, sudden withdrawal from alcohol following regular or chronic use can also increase your risk of seizures during treatment with buPROPion. Version: 24.01.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. In general, you should avoid or limit the use of alcohol while being treated with buPROPion. Do not stop using any medications without first talking to your doctor.Applies to: Robitussin Nighttime Cough DM (dextromethorphan / doxylamine)Alcohol can increase the nervous system side effects of doxylamine such as dizziness, drowsiness, and difficulty concentrating. Why Are Dementia Patients Getting Risky Psychiatric Drugs? If you take these drugs with cough medicine, some decongestants, or an antihistamine, the sedating effect can be intensified. Drinking alcohol with Wellbutrin XL may increase your risk of seizures. Contact your doctor if you experience increased side effects or your condition changes. Your reactions could be impaired.Report any new or worsening symptoms to your doctor, such as: mood or behavior changes, a manic episode--racing thoughts, increased energy, reckless behavior, feeling extremely happy or irritable, talking more than usual, severe problems with sleep.This is not a complete list of side effects and others may occur. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. buPROPion dextromethorphan Applies to: Wellbutrin XL (bupropion) and Robitussin Nighttime Cough DM (dextromethorphan / doxylamine) BuPROPion may increase the blood levels and effects of dextromethorphan. Dextromethorphan is an active ingredient in Robitussin, Delsym, and other over-the-counter cough suppressants. Yesterday morning I took 150mg Wellbutrin and 2 teaspoons of Delsym cough syrup and within an hour I was feeling dizzy (sort of out of it). Too much of this medicine can increase your risk of a seizure.You should not change your dose or stop using Wellbutrin XL suddenly, unless you have a seizure while taking this medicine. MAO inhibitors include isocarboxazid, linezolid, phenelzine, rasagiline, selegiline, and tranylcypromine.Do not take Wellbutrin XL to treat more than one condition at a time. Talk to your doctor if you have trouble quitting after taking Zyban for 7 to 12 weeks.Some people taking Wellbutrin XL (Wellbutrin or Zyban) have had high blood pressure that is severe, especially when also using a nicotine replacement product (patch or gum).