Copyright © 2018 by RxList Inc. RxList does not provide medical advice, diagnosis or treatment. Anyone who ahs concerns about this medication or wonders if it’s right for their pet should talk to an animal health expert to evaluate the specific risks and benefits for their situation. The intramuscular administration of oxytetracycline produces lower Terramycin (oxytetracycline) Intramuscular Solution is available as follows: 250 mg/2ml in 2 ml pre-scored glass ampules, packages of 5 (NDC 0049-0770-09). It is taken by mouth. for a total of 9.0 grams.For treatment of syphilis, a total of 30–40 grams in equally divided doses over a period of 10–15 days should be given. No abnormalities of thyroid function studies are known to occur.Adults: Usual daily dose, 1–2 g divided in four equal doses, depending on the severity of the infection.For children above eight years of age: Usual daily dose, 10–20 mg per pound (25–50 mg/kg) of body weight divided in four equal doses.Therapy should be continued for at least 24–48 hours after symptoms and fever have subsided.For treatment of brucellosis, 500 mg oxytetracycline four times daily for 3 weeks should be accompanied by streptomycin, 1 gram intramuscularly twice daily the first week, and once daily the second week.For treatment of uncomplicated gonorrhea, when penicillin is contraindicated, tetracycline may be used for the treatment of both males and females in the following divided dosage schedule: 1.5 grams initially followed by 0.5 gram q.i.d. If the Kirby-Bauer method of disc susceptibility testing is used, a 30 mcg tetracycline disc should give a zone of at least 19 mm when tested against a tetracycline-susceptible bacterial strain.Tetracyclines are readily absorbed and are bound to plasma proteins in varying degree. This medicine may cause teeth discoloration in the children. (See Skin: maculopapular and erythematous rashes. Tobramycin works by killing bacteria.. Ophthalmic tobramycin may be used alone or with other medicines for eye infections. If superinfection occurs, the antibiotic should be discontinued and appropriate therapy instituted.In venereal diseases when coexistent syphilis is suspected, a dark field examination should be done before treatment is started and the blood serology repeated monthly for at least 4 months.Because tetracyclines have been shown to depress plasma prothrombin activity, patients who are on anticoagulant therapy may require downward adjustment of their anticoagulant dosage.In long term therapy, periodic laboratory evaluation of organ systems, including hematopoietic, renal and hepatic studies should be performed.All infections due to Group A beta-hemolytic streptococci should be treated for at least 10 days.Since bacteriostatic drugs may interfere with the bactericidal action of penicillin, it is advisable to avoid giving tetracycline in conjunction with penicillin.Gastrointestinal: anorexia, nausea, vomiting, diarrhea, glossitis, dysphagia, enterocolitis, and inflammatory lesions (with monilial overgrowth) in the anogenital region. (See Hypersensitivity reactions: Urticaria, angioneurotic edema, anaphylaxis, anaphylactoid purpura, pericarditis and exacerbation of systemic lupus erythematosus.Bulging fontanels in infants and benign intracranial hypertension in adults have been reported in individuals receiving full therapeutic dosages. not only in animal eyes? Trace amounts of the drug are present in the yolks laid months after treatment has stopped. Chlamydia Infection. Oral forms of tetracyclines should be given 1 hour before or 2 hours after meals. Oxytetracycline is active against a wide range of gram-negative and gram-positive organisms. Eye infections often impact animals more than they do people, in part because the anatomy of most small creatures means that their eyes are more likely to come into contact with bacteria on the ground or in the environment. Oxytetracycline is primarily bacteriostatic and is thought to exert its antimicrobial effect by the inhibition of protein synthesis. Tetracyclines are readily absorbed and are bound to You are encouraged to report negative side effects of prescription drugs to the FDA. This reaction was shown to be reversible when the drug was discontinued.Tetracyclines are present in the milk of lactating women who are taking a drug in this class.As with other antibiotic preparations, use of this drug may result in overgrowth of nonsusceptible organisms, including fungi. Terramycin® ophthalmic ointment is one of the options available in many places. Enamel hypoplasia has also been reported. (minimum inhibitory concentration) is not more than 4.0 mcg/ml and intermediate if the M.I.C. Common side effects of Terramycin (oxytetracycline) include: Evidence of embryotoxicity has also been noted in animals treated early in pregnancy.All tetracyclines form a stable calcium complex in any bone forming tissue.