What should I say to my doctor at my next appointment?I've always taken Zofran early on in my migraine, right when I start feeling nauseas and it usually helps to settle my stomach. Revision date: November 5, 2019.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Available for Android and iOS devices. Ask about antiemetics that are dissolvable in the mouth or suppositories. Allow it to dissolve in your mouth without chewing.Measure liquid medicine with the dosing syringe provided, or with a special dose-measuring spoon or medicine cup. Tell your doctor if you are pregnant.It is not known whether ondansetron passes into breast milk or if it could harm a nursing baby. The most frequently reported side effects are headache, constipation, and diarrhea. He suggested that in the future the instant I feel a slight headache coming on to take regular Tylenol right … … You should refer to the prescribing information for Zofran for a complete list of interactions.Zofran (ondansetron). We comply with the HONcode standard for trustworthy health information - It’s mainly designed for cancer patients who have nausea associated with chemo. Effectiveness of Greater Occipital Nerve Blocks in Migraine Prophylaxis. That said, I found zofran to be more effective when taken earlier so it has time to kick in. Skip the missed dose if it is almost time for your next scheduled dose. Headaches are a side-effect of Zofran, and my doc told me it was safe to take Tylenol to help alleviate it. Select one or more newsletters to continue. The next migraine I had, I took my imitrex, started to feel sick to my stomach, so I popped in a zofran.I vomited about seven times, and my imitrex didn't seem to help at all. Ondansetron is a 5-hydroxytyptamine (5-HT) type 3 receptor antagonist drug commonly used for the prophylaxis and treatment of PONV.2 Headache is the most commonly reported side effect of ondansetron.3 The exact mechanism of ondansetron-induced headache is not known; a weak 5-HT1 antagonistic effect may precipitate headache in susceptible individuals, including migraine sufferers … Magnesium helps relieve headaches, promotes muscle relaxation, and reduces anxiety. If you are between the ages of 18 and 60, take no other medication or have no other medical conditions, side effects you are more likely to experience include:Notes: In general, seniors or children, people with certain medical conditions (such as liver or kidney problems, heart disease, diabetes, seizures) or people who take other medications are more at risk of developing a wider range of side effects. We comply with the HONcode standard for trustworthy health information - GlaxoSmithKline LLC Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Zofran only for the indication prescribed.Copyright 1996-2020 Drugs.com. It is used a lot with chemotherapy patients and is given post-op to decrease the risk of nausea from anesthesia. Zofran is a medication that prevents and treats nausea and vomiting. Town Center Location What is Zofran? You may report side effects to FDA at 1-800-FDA-1088.Zofran can cause a serious heart problem, especially if you use certain medicines at the same time, including antibiotics, antidepressants, heart rhythm medicine, antipsychotic medicines, and medicines to treat cancer, malaria, HIV or AIDS.