Generic name: TAZOBACTAM SODIUM 0.375g in 15mL, PIPERACILLIN SODIUM 3g in 15mLZOSYN should be administered by intravenous infusion over 30 minutes.The usual total daily dose of ZOSYN for adults is 3.375 g every six hours totaling 13.5 g (12.0 g piperacillin/1.5 g tazobactam). bags or cartridge). Prescription drugs from Canada and U.S.A. paired with equivalent drugs from Mexico. Drugs presented in several formats for ease of location. Advate may be available with PA in cases of large volume dosing in patients with poor venous access. For children with appendicitis and/or peritonitis 9 months of age or older, weighing up to 40 kg, and with normal renal function, the recommended ZOSYN dosage is 100 mg piperacillin/12.5 mg tazobactam per kilogram of body weight, every 8 hours. Swirl until dissolved.Reconstituted ZOSYN solutions for both bulk and single dose vials should be further diluted (recommended volume per dose of 50 mL to 150 mL) in a compatible intravenous solution listed below. It should be injected slowly over at least 30 minutes. Compatibility of ZOSYN with other aminoglycosides has not been established.Parenteral drug products should be inspected visually for particulate matter and discoloration prior to administration, whenever solution and container permit.Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Simultaneous co-administration via Y-site infusion in any manner other than listed above may result in inactivation of the aminoglycoside by ZOSYN.ZOSYN is not compatible with tobramycin for simultaneous co-administration via Y-site infusion. For pediatric patients between 2 months and 9 months of age, the recommended ZOSYN dosage based on pharmacokinetic modeling, is 80 mg piperacillin/10 mg tazobactam per kilogram of body weight, every 8 hours [It has not been determined how to adjust ZOSYN dosage in pediatric patients with renal impairment.Reconstituted stock solution must be transferred and further diluted for intravenous infusion.The pharmacy bulk vial is for use in a hospital pharmacy admixture service only under a laminar flow hood. During the infusion it is desirable to discontinue the primary infusion solution.ZOSYN should not be mixed with other drugs in a syringe or infusion bottle since compatibility has not been established.ZOSYN is not chemically stable in solutions that contain only sodium bicarbonate and solutions that significantly alter the pH.ZOSYN should not be added to blood products or albumin hydrolysates. Discard unused portion after 24 hours if stored at room temperature (20°C to 25°C [68°F to 77°F]), or after 48 hours if stored at refrigerated temperature (2°C to 8°C [36°F to 46°F]).Reconstitute the pharmacy bulk vial with exactly 152 mL of a compatible reconstitution diluent, listed below, to a concentration of 200 mg/mL of piperacillin and 25 mg/mL of tazobactam. If you notice other effects not listed above, contact your doctor or pharmacist.Call your doctor for medical advice about side effects. These are amino acids in which the amino group is attached to the carbon atom immediately adjacent to the carboxylate group (alpha carbon), or a derivative thereof.Tazobactam is a drug which is used in combination with piperacillin to … ZOSYN contains no preservatives. oral agents, (2) the advent of newer, more potent, broad-spec-trum oral agents that achieve high-er and more consistent serum and tissue concentrations, and (3) the availability of randomized clinical trials comparing various IV and oral therapeutic strategies. DIABETIC -ORAL BIGUANIDES METFORMIN HCL TABS LISINOPRIL TABS ACCUPRIL TABS ... ZOSYN CEPHALOSPORINS 2. Discard any unused portion after 24 hours if stored at room temperature (20°C to 25°C [68°F to 77°F]), or after 48 hours if stored at refrigerated temperature (2°C to 8°C [36°F to 46°F]). [44289] Guidelines recommend piperacillin; tazobactam as part of combination therapy for hospitalized patients with prior respiratory isolation of P. aeruginosa or risk factors for P. … This copyrighted material has been downloaded from a licensed data provider and is not for distribution, except as may be authorized by the applicable terms of use.Things to remember when you fill your prescription.WebMD does not provide medical advice, diagnosis or treatment.This survey is being conducted by the WebMD marketing sciences department.All information will be used in a manner consistent with the WebMD Consult your pharmacist or local waste disposal company.Information last revised April 2020. Visit athenaInsight for proven, replicable best practices and data-driven strategies to enhance your practice's performance: