Other medications can decrease the effectiveness of Zyprexa or increase the risk of side effects. Your doctor may decide not to treat you with this medication or change some of the other medicines you take.Using this medicine with any of the following medicines is usually not recommended, but may be required in some cases. Make sure you tell your doctor if you have any other medical problems, especially:Portions of this document last updated: Sept. 01, 2020Copyright © 2020 IBM Watson Health. All rights reserved. While all agents in the class have been shown to produce some changes, each drug has its own specific risk profile. Olanzapine Interactions with Food and Herbs Grapefruit and Juice: Grapefruit and grapefruit juice interact with olanzapine and can lead to potentially dangerous side effects. Selected from data included with permission and copyrighted by First Databank, Inc. Patients with diabetes should be monitored for worsening control of blood glucose when treated with these agents. It should not be used for medical advice, diagnosis or treatment. Do not use more than the recommended dose of OLANZapine, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Some people may also experience impairment in thinking and judgment. We comply with the HONcode standard for trustworthy health information - Talk to your doctor or pharmacist if you have any questions or concerns.Hyperglycemia, in some cases extreme and associated with ketoacidosis or hyperosmolar coma or death, has been reported with the use of atypical antipsychotic agents. Appropriate studies performed to date have not demonstrated geriatric-specific problems that would limit the usefulness of olanzapine in the elderly. Advertising revenue supports our not-for-profit mission.Check out these best-sellers and special offers on books and newsletters from Mayo Clinic. Moderate Food Interaction Alcohol can increase the nervous system side effects of OLANZapine such as dizziness, drowsiness, and difficulty concentrating. • Carbamazepine:Increased clearance of olanzapine. PRECAUTIONS: Before taking olanzapine, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies.This product may contain inactive ingredients, which can cause allergic reactions or other problems. Patient Information Sheet: Olanzapine (marketed as Zyprexa) This is a summary of the most important information about Zyprexa provided by the FDA. Also tell your health care professional if you have any other types of allergies, such as to foods, dyes, preservatives, or animals. Typically patients begin at a low dose of medicine and the dose is increased slowly over several weeks. Drug interactions are reported among people who take Zyprexa and Cannabis together. If you are taking Zyprexa, talk to your doctor before drinking grapefruit juice or eating grapefruit. Some people may also experience impairment in thinking and judgment. All rights reserved. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. When treating pediatric patients with atypical antipsychotic agents, weight gain should be monitored and assessed against that expected for normal growth. Other Interactions . In some cases, hyperglycemia has resolved when treatment with these agents was discontinued; however, some patients required continuation of anti-diabetic treatment despite discontinuation of the atypical antipsychotic drug.Atypical antipsychotic drugs have been associated with undesirable alterations in lipid levels. You should avoid or … We comply with the HONcode standard for trustworthy health information - The study is created by eHealthMe based on reports of 465 people who take Coumadin and Zyprexa from the Food and Drug Administration (FDA), and is updated regularly. ... Are There Any Interactions With Drugs or Foods? Patients who develop symptoms of hyperglycemia during treatment with atypical antipsychotics should undergo fasting blood glucose testing.