Diabetes insipidus centralis was suspected and treatment with DDAVP initiated. 1995 Sep;29(3):172-91. doi: 10.2165/00003088-199529030-00004. Amiloride administration was also associated with a significant increase in urine osmolality (from 575±54 to 699±48 mOsm per kilogram of HWe conclude that amiloride mitigates lithium-induced polyuria, at least partly, by blunting the inhibitory effect of lithium on water transport in the renal collecting tubule. Prepare to become a physician, build your knowledge, lead a health care organization, and advance your career with NEJM Group information and services.Vasopressin-resistant diabetes insipidus is a common side effect of the treatment of affective disorders with lithium. Congenital nephrogenic diabetes insipidus (NDI) is a rare inherited disorder, mostly caused by AVPR2 mutations. 2000 Mar;16(3):165-77. doi: 10.2165/00002512-200016030-00002.Clin Pharmacokinet. (N Engl J Med 1985; 312:408–14. Diagnosis and management of this condition remain challenging especially during infancy. 1981;7(2):67-73. doi: 10.1159/000117833.Jobbagy S, Vitturi DA, Salvatore SR, Pires MF, Rowart P, Emlet DR, Ross M, Hahn S, St Croix C, Wendell SG, Subramanya AR, Straub AC, Tan RJ, Schopfer FJ.JCI Insight. Unable to load your delegates due to an error
Concise summaries and expert physician commentary that busy clinicians need to enhance patient care.The most effective and engaging way for clinicians to learn, improve their practice, and prepare for board exams.NEW! Treatment of nephrogenic diabetes insipidus with hydrochlorothiazide and amiloride Veronika Kirchlechner, Dieter Y Koller, Reiner Seidl, Franz Waldhauser Abstract Nephrogenic diabetes insipidus (NDI) is characterised by the inability of the kidney to concentrate urine in response to arginine vasopressin. Clipboard, Search History, and several other advanced features are temporarily unavailable. doi: 10.1172/jci.insight.128578.Clin Pharmacokinet. Amiloride-hydrochlorothiazide versus indomethacin-hydrochlorothiazide in the treatment of nephrogenic diabetes insipidus N. Knoers, MD, and L. A. H. Monnens, MD, PhD From the Departments of Pediatrics and Human Genetics, Catholic University, Nijmegen, The Netherlands Several studies1"3 have demonstrated that the combination of … Unable to load your collection due to an error Because the boy continued to suffer from polyuria with low urinary osmolality, a dehydration test with subsequent DDAVP administration was performed and the diagnosis of NDI was established. One of the major side effects of lithium is nephrogenic diabetes insipidus. One of the major side effects of lithium is nephrogenic diabetes insipidus. COVID-19 is an emerging, rapidly evolving situation. Background and objectives: Polyuria, polydipsia, and nephrogenic diabetes insipidus have been associated with use of psychotropic medications, especially lithium.
2016 Aug;55(8):925-41. doi: 10.1007/s40262-016-0370-y.CNS Drugs. Atypon Abstract Vasopressin-resistant diabetes insipidus is a common side effect of the treatment of affective disorders with lithium. The suggested doses are 5mg twice a day, and can be combined with … 1985 Feb 14;312(7):408-14. doi: 10.1056/NEJM198502143120705.Am J Kidney Dis. 1987 Nov;10(5):329-45. doi: 10.1016/s0272-6386(87)80098-7.Pharmacotherapy. We studied the effect of amiloride on lithium-induced polyuria in nine such patients receiving maintenance lithium therapy who had a vasopressin-resistant defect in urinary concentrating ability. Please enable it to take advantage of the complete set of features!
… To the Editor: Although the exact mechanism of the antidiuresis demonstrated by Batlle et al.
2020 Jan 16;5(1):e128578. 2003 Apr;23(4):546-50. doi: 10.1592/phco.23.4.546.32121.Hosp Community Psychiatry.