Women treated with cyclophosphamide injection may go through menopause at a younger age than normal. It is the hydrochloride salt of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl) piperazine and its structural formula is:Molecular formula C19H21N5O4•HClIt is a white, crystalline substance, slightly soluble in water and isotonic saline, and has a molecular weight of 419.87. Pregnancy. The therapeutic dosages most commonly employed have ranged from 6 mg to 15 mg daily given in divided doses.
In these instances, the exact causal relationship has not been established because the baseline observations were frequently inadequate.In more specific slit-lamp and funduscopic studies, which included adequate baseline examinations, no drug-related abnormal ophthalmological findings have been reported.Literature reports exist associating Minipress therapy with a worsening of pre-existing narcolepsy. It is the hydrochloride salt of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl) piperazine and its structural formula is:
In most instances, side effects have disappeared with continued therapy or have been tolerated with no decrease in dose of drug.Less frequent adverse reactions which are reported to occur in 1–4% of patients are:In addition, fewer than 1% of patients have reported the following (in some instances, exact causal relationships have not been established):Single reports of pigmentary mottling and serous retinopathy, and a few reports of cataract development or disappearance have been reported. Many patients will require more than one drug to achieve blood pressure goals. The results of dog forelimb experiments demonstrate that the peripheral vasodilator effect of prazosin is confined mainly to the level of the resistance vessels (arterioles). Recent animal studies, however, have suggested that the vasodilator effect of prazosin is also related to blockade of postsynaptic alpha-adrenoceptors. In addition, 27 males on Minipress for up to 51 months did not have changes in sperm morphology suggestive of drug effect.Minipress has been shown to be associated with decreased litter size at birth, 1, 4, and 21 days of age in rats when given doses more than 225 times the usual maximum recommended human dose. Minipress should be used during pregnancy only if the potential benefit justifies the potential risk to the mother and fetus.Minipress has been shown to be excreted in small amounts in human milk. Restoration of blood pressure and normalization of heart rate may be accomplished by keeping the patient in the supine position.
Cyclophosphamide belongs to a class of drugs known as nitrogen mustard-based agents. Check with your Cyclophosphamide has no known severe interactions with other drugs.Cyclophosphamide has moderate/mild interactions with at least 56 different drugs.This information does not contain all possible interactions or adverse effects. Do not take Cytoxan if you are allergic to cyclophosphamide or any ingredients contained in this drug.Keep out of reach of children. During these trials and subsequent marketing experience, the most frequent reactions associated with Minipress therapy are: dizziness 10.3%, headache 7.8%, drowsiness 7.6%, lack of energy 6.9%, weakness 6.5%, palpitations 5.3%, and nausea 4.9%. As chemotherapy it is used to treat lymphoma, multiple myeloma, leukemia, ovarian cancer, breast cancer, small cell lung cancer, neuroblastoma, and sarcoma. Auf der Suche nach einem Kre… In der Rubrik Test & Quiz sowie in den Diskussionsforen können Sie schließlich selbst aktiv werden!Die Informationen dürfen auf keinen Fall als Ersatz für professionelle Beratung oder Behandlung durch ausgebildete und anerkannte Ärzte angesehen werden.
Außerdem kommt es oftmals zu Häufige Cyclophosphamid-Nebenwirkungen sind auch Infektionen, Einige Nebenwirkungen wie die Übelkeit lassen sich mit der Einnahme weiterer Wirkstoffe abmildern.Das Chemotherapeutikum Cyclophosphamid geht zahlreiche Wechselwirkungen mit anderen Arzneistoffen ein, besonders solchen, die in der Leber ab- oder umgebaut werden und damit die Aktivierung von Cyclophosphamid beeinflussen.Bestimmte Medikamente können die Aktivierung von Cyclophosphamid hemmen und dessen Wirksamkeit dadurch vermindern.
Alkylating agents are so named because of their ability to add alkyl groups to many electronegative groups under conditions present in cells. It is the hydrochloride salt of 1-(4-amino-6,7-dimethoxy-2-quinazolinyl)-4-(2-furoyl) piperazine and its structural formula is:It is a white, crystalline substance, slightly soluble in water and isotonic saline, and has a molecular weight of 419.87. Außerdem bieten wir hilfreiche Informationen zu Ihrem Arztbesuch, indem wir über Behandlungen und Untersuchungen … These considerations may guide selection of therapy.Minipress can be used alone or in combination with other antihypertensive drugs such as diuretics or beta-adrenergic blocking agents.Minipress is contraindicated in patients with known sensitivity to quinazolines, prazosin, or any of the inert ingredients.If syncope occurs, the patient should be placed in the recumbent position and treated supportively as necessary.